Therapeutics A Highly-Efficient Platform To Form Vesicular Polymer Nanoparticles For RNA And Protein Payload Delivery Polymersomes are a type of nanoscale vesicle made from block copolymers and can encapsulate a variety of therapeutic agents including proteins and nucleic acids.… Interests: Drug Delivery, Gene Therapy, Infectious Disease, Oncology, Vaccines Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Novel Antibody Drug Conjugate To Improve Cancer Therapy Efficacy A novel antibody-drug conjugate (ADC) with a lactate-responsive linker, enhancing therapeutic specificity by remaining stable in healthy tissues and releasing its therapeutic payload in… Interests: Antibody, Drug Delivery, Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Novel Small Molecules For Treatment Of Breast and Ovarian Cancer According to the National Osteoporosis Foundation (NOF) approximately 10.2 million adults in the United States have osteoporosis, with an additional 43.4 million having low… Interests: Oncology, Small Molecules Desired Partnership: Co-development, Licensing IP: Patent Pending
Agricultural Diagnostics Therapeutics In Vitro Assay To Select Optimal Small RNA Guides To Redirect ADAR (Adenosine Deaminase That Acts On RNA) Enzymes A breakthrough method to systematically select for optimal small guide RNAs using an unbiased approach for improved accuracy and efficiency of all systems of… Interests: Biologics, Drug Development Tool, Gene Therapy Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Multihydroxy-Propane Vesicle System and Method for Topical Delivery of mRNA Groundbreaking advancement in the field of mRNA topical delivery systems, providing superior penetration, stability, and biocompatibility compared to existing solutions. It opens up new… Interests: Dermatology, Drug Delivery, Gene Therapy, Wound Healing Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Expanding CAR T Cells Using Venetoclax For Enhanced Cytolytic Activity Against Tumors Expanding CAR T cells with venetoclax enhances their ability to target and kill CD19+ tumor cells, increases their effectiveness, and reduces exhaustion, potentially leading… Interests: New Chemical Entity, Small Molecules Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials Research Tools Therapeutics Scalable Bioelectronic Production Of Extracellular Vesicles For Regenerative Medicine Bioelectronic devices and methods for the electrical stimulation of cells and engineered tissue for the scalable production of extracellular vesicles for drug delivery and… Interests: Medical, Stem Cell Therapy Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Programmed RNA Editing with an Evolved Bacterial Adenosine Deaminase A novel platform, bacterial deaminase-enabled recoding of RNA (DECOR), utilizing an engineered bacterial adenosine deaminase to achieve programmable adenosine-to-inosine (A-to-I) editing on single-stranded RNA.… Interests: Gene Therapy Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Engineered Flt3L Variants For Antigen Tolerance Induction Engineered recombinant fusion of the dendritic cell growth factor Flt3L to serum albumin to modulate the antigen-presenting compartment and bias it toward tolerance particularly… Interests: Antibody, Autoimmune, Inflammatory Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Engineered Cytokine-Receptor System For Enhanced Cancer And Viral Infection Treatment The technology enhances cytokine signaling and immune function, optimizing the antiviral and anti-cancer efficacy of Type III IFNs by adjusting cytokine-receptor interaction affinity and… Interests: Infectious Disease, Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics RNA-Guided Control Of Protein Secretion And Membrane Protein Expression Innovative methods to engineer small nucleolar RNAs to target specific mRNAs to increase or decrease the secretion of desired proteins offering scalable solutions for… Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Targeting the BRCA1 Pseudogene (BRCA1P1) to Inhibit Cancer Progression and Increase Therapy Responses Compositions and methods to target long non-coding RNA (lncRNA) from the BRCA1 pseudogene in breast cancer cells to stimulate the body’s natural immune response,… Interests: Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
