Bioinformatics

New Reversible Uridine Modification Chemistry For Labeling and Functionalizing Native Nucleic Acids

SUMMARY A chemical process that enables reversible, covalent RNA modification-highly selective for uridine enabling diverse functional group attachment, facilitating nucleic acid labeling The Unmet Need: Reversible labeling of native RNA in a sequence-independent and membrane-selective manner   The study… Read More

AI Pipeline For Predicting Oral Cancer Progression

SUMMARY An AI-driven system analyzes histopathology images of oral lesions using deep learning, self-supervised learning, and attention methods to predict cancer progression risk with explainable and uncertainty-quantified outputs that inform treatment decisions. The Unmet Need: Automated and accurate malignancy prediction tools The… Read More

Machine Learning-Based Prediction Of Viral Mutations From Genomic Sequences

SUMMARY Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide.  In the United States, there are 1.1 million burn injuries which require medical attention each year.  These injuries often result in significant scarring having a negative impact on the… Read More