Research Tools Therapeutics Evolved riboflavin biosynthesis enzyme RibD as a novel nucleic acid deaminase for base editing. Enhanced precision in cytosine base editing by employing an evolved riboflavin biosynthesis enzyme RibD that converts targeted cytosines to thymines without intrinsic sequence-context specificity,… Interests: Gene Therapy Reference ID: 25-T-022
Research Tools Conformation-Specific HLA-F Antibodies Enable Next-Generation Immune Profiling A panel of antibody-based reagents has been developed to distinguish two conformational states of the nonclassical MHC protein HLA-F: an open conformer form and… Interests: Antibody, Biomarker, Drug Development Tool Reference ID: 22-T-062
Diagnostics Research Tools Integration Of Semiconductor-Based Components And Functionality Into Soft Microfluidics For Cell Lysis And Other Biological Applications This technology delivers precise and scalable cellular content extraction for genomic analyses by integrating semiconductor-based piezoelectric sharp tip arrays into soft microfluidics, enabling efficient… Reference ID: 21-T-034
Research Tools Improved Ex Vivo Models Of Pancreatic Cancer Using Tumor-Relevant Nutrient Conditions Tumor Interstitial Fluid Medium (TIFM) is a pancreatic tumor-mimetic cell culture formulation, paired with matched murine PDAC cell lines adapted in either TIFM or… Interests: Cell Line, Tangible Property Reference ID: 24-T-063
Agricultural Cleantech Medical Devices Research Tools Therapeutics Adaptive Microbial Platform For Gut Health, Biofuel, And Soil Productivity A novel biomaterial platform designed to enhance microbial modulation, featuring tunable chemical, mechanical, and optical responsiveness for applications in health, agriculture, and industry. The… Interests: Chemical Synthesis, Medical, Microbiome Reference ID: 23-T-052
Research Tools Therapeutics Rapid Selection Of High-Value Internalizing Binders For Targeted Therapeutics Lentiviral display platform engineered to directly select and enrich antibodies based on their ability to induce receptor-mediated endocytosis, thereby streamlining the discovery of highly… Interests: Antibody, Antibody Reference ID: 26-T-188 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics A Programmable Translational Activator Platform For Restoring Endogenous Protein Expression In Haploinsufficiency Disorders The CIRTS-4GT3 platform is a compact, programmable system that uses guide RNAs and human protein domains to boost production of specific proteins in cells,… Interests: Gene Therapy Reference ID: 24-T-204 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Nucleic Acid Enrichment And Sequencing Method For Detecting Off-Target Base Editing Events Inrich-seq is a new method that selectively enriches and sequences inosine-containing DNA or RNA, enabling highly sensitive, genome-wide detection of off-target effects from adenine… Interests: Drug Screening, Gene Therapy Reference ID: 25-T-225 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling… Reference ID: 24-T-049 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV… Interests: Gene Therapy, Genomics Reference ID: 23-T-046 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC… Interests: Drug Development Tool, Drug Screening, Drug Target, Oncology Reference ID: 26-T-081 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Glycan Proximity Sequencing (GPS) For Single-Cell Multi-omics Glycoproteomics TL;DR: Glycan Proximity Sequencing (GPS) is a next-generation single-cell multi-omics assay that measures mRNA expression, extracellular protein abundance, global glycan motifs, and protein-specific glycoforms… Interests: Biomarker Reference ID: 26-T-004 Desired Partnership: Co-development, Licensing IP: Patent Pending
