Tangible Property

Reversible Gene Editing System For Site-Specific Large DNA Integration And Excision

SUMMARY Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide.  In the United States, there are 1.1 million burn injuries which require medical attention each year.  These injuries often result in significant scarring having a negative impact on the… Read More

A Versatile and High-throughput Assay for the Directed Evolution of Reverse Transcriptases to Profile Epigenetic Modifications With NGS

SUMMARY Engineered reverse transcriptases (RTs) to profile epigenetic modifications have numerous advantages over traditional antibody enrichment methods including: single base pair resolution, lower sample quantities needed, and lower noise and background interference. Problematically, current RT engineering strategies are cumbersome, low throughput, and cannot be versatilely applied to multiple types of… Read More