SUMMARY A Sindbis virus-based self-amplifying RNA vector has been engineered for long-lasting, safe gene expression in skin cells, aiming to treat genetic skin disorders like recessive X-linked ichthyosis by restoring missing genes with improved durability and reduced side effects. The Unmet… Read More
SUMMARY A portable device that generates and stores molecular hydrogen within a hydrogel using electrodes to precisely deliver hydrogen locally to treat oxidative stress in skin diseases and ischemia-reperfusion injuries The Unmet Need: Precise and efficient methods to deliver molecular hydrogen to… Read More
SUMMARY Groundbreaking advancement in the field of mRNA topical delivery systems, providing superior penetration, stability, and biocompatibility compared to existing solutions. It opens up new possibilities for both therapeutic and cosmetic applications, paving the way for more effective and user-friendly treatments. The unmet… Read More
SUMMARY Appearance of ulcers and slow wound healing are a hallmark symptom of several autoimmune disorders including type II diabetes. Current treatment approaches rely on antiquated bandaging, however bulkiness and inconvenience often result in low patient compliance. Growth factor-based therapies have demonstrated promise in clinical trials, but the high dosing… Read More