Diagnostics Research Tools Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling… Reference ID: 24-T-049 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV… Interests: Gene Therapy, Genomics Reference ID: 23-T-046 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC… Interests: Drug Development Tool, Drug Screening, Drug Target, Oncology Reference ID: 26-T-081 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Glycan Proximity Sequencing (GPS) For Single-Cell Multi-omics Glycoproteomics TL;DR: Glycan Proximity Sequencing (GPS) is a next-generation single-cell multi-omics assay that measures mRNA expression, extracellular protein abundance, global glycan motifs, and protein-specific glycoforms… Interests: Biomarker Reference ID: 26-T-004 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Antibody-Based Cell Expansion Technology For Large-Scale And Safe Amplification Of Gamma Delta T Cells Novel antibodies to rapidly and safely expand γδ T cells enabling large-scale production for cancer immunotherapies like γδ CAR-T cells, and potentially boosting these… Interests: Antibody, Antibody, Biologics, Drug Development Tool, Oncology Reference ID: 26-T-031 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Therapeutics New Reversible Uridine Modification Chemistry For Labeling and Functionalizing Native Nucleic Acids A chemical process that enables reversible, covalent RNA modification-highly selective for uridine enabling diverse functional group attachment, facilitating nucleic acid labeling The Unmet Need:… Interests: Bioinformatics, Biologics, Biomarker, Chemical Synthesis, Chemical Synthesis, Drug Delivery, Genomics, Imaging Agents, Medical, New Chemical Entity, Sequencing Reference ID: 25-T-126 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics Prolactin Receptor Antibodies For Targeted Cancer Therapy And Diagnosis Novel antibodies precisely targeting cancer cells by binding to the Prolactin Receptor (PRLR) to diagnose cancer, direct immune cells to destroy tumors, and inhibit… Interests: Antibody, Oncology Reference ID: 25-T-104 Desired Partnership: Co-development, Licensing IP: Patent Pending
Quantum Sciences Research Tools Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes Quantum nanoprobe system enables real-time probing of intracellular chemical environments and activity to advance biological and medical diagnostics The Unmet Need: Novel ways to… Interests: Drug Development Tool, Drug Screening, Sensing Reference ID: 25-T-106 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools A High-Throughput, Label-Free Microfluidic System For Combinatorial Droplet Generation, Storage, And Analysis A microfluidic platform consisting of a two-layer PDMS system that generates and stores combinatorial droplets, enabling high-throughput screening with an integrated label-free, image-based detection… Reference ID: 25-T-014 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Conformation-Specific Genetically Encodable Intrabodies for Spatially Modulating Protein Kinase Signaling Genetically encoded synthetic antibody fragments, expressed intracellularly, to specifically bind the mTOR FKBP12-Rapamycin binding domain inhibiting mTORC1 and mTORC2 activity. Fused with localization signals,… Interests: Antibody, Drug Development Tool Reference ID: 25-T-060 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Bioorthogonal Enzyme-Probe System For Spatially Specific Biomolecule Labeling Novel proximity labeling technology utilizes a bioorthogonal protecting group, impervious to endogenous esterases, paired with evolved BS2 esterase mutants. The enzyme-mediated unmasking creates a… Interests: Drug Development Tool Reference ID: 25-T-114 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Reversible Gene Editing System For Site-Specific Large DNA Integration And Excision The Unmet Need: Methods for efficient, reversible integration and excision of large DNA Genome engineering is a rapidly advancing field with immense potential for… Interests: Biologics, Gene Therapy, Infectious Disease, Tangible Property Reference ID: 25-T-198 Desired Partnership: Co-development, Licensing IP: Patent Pending