Therapeutics Gene Splice-Switching Technology for Treating CACNA1A-Associated Neurological Diseases This technology regulates the expression of the CACNA1A gene, which encodes a neuronal calcium channel subunit, by redirecting alternative splicing to treat related neurological… Interests: Musculoskeletal, Neurology, Rare/Orphan Diseases Reference ID: 24-T-060 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Engineered Mutator tRNAs For Correcting Missense Genetic Defects And Inducing Cancer Cell Death Engineered tRNAs with altered anticodons and chemical modifications deliver the correct amino acid at mutated codons to restore protein function in genetic diseases or… Interests: Biologics, Oncology Reference ID: 22-T-111 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Low-Input Methylation Sequencing For Profiling Epitranscriptomic Signatures And Early Colorectal Cancer Diagnosis A method that analyzes cfRNA methylation in plasma to distinguish human RNA from microbiome RNA, accurately detecting colorectal cancer through specific methylation markers even… Interests: Epigenetics, Microbiology/Virology, Sequencing Reference ID: 24-T-187 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Antibody-Based Therapeutics For Inhibiting Growth Hormone Receptor Dimerization And Signaling Antibodies that block growth hormone signaling by binding the receptor or hormone to stop receptor pairing, based on high-affinity, defined sequences for therapeutic and… Interests: Antibody, Rare/Orphan Diseases Reference ID: 23-T-100 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Computerized Adaptive Testing System For Real-Time Multidimensional Fatigability Assessment A computerized adaptive test using a bifactor model on tablet devices to measure fatigue relative to activity delivering personalized, real-time insights by integrating with… Reference ID: 25-T-089 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Synthetic Monoclonal Antibodies For Blocking Human Growth Hormone Receptor Signaling Synthetic monoclonal antibodies using phage display to bind and block the human growth hormone receptor, potentially offering a more potent and specific treatment for… Interests: Antibody, Rare/Orphan Diseases Reference ID: 22-T-001 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Software Computational Framework For Unraveling Single-Cell Transcriptional Dynamics Novel system using statistical topic modeling and a bursty transcriptional model to analyze spliced and unspliced RNA, revealing precise cell state transitions and dynamics… Reference ID: 22-T-208 Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices AI-Based Ultrasound Analysis System For Automated Segmentation And Classification Of Adnexal Lesions AI-driven system automatically segments adnexal masses in ultrasound images, distinguishes different tissue components, and extracts key features to accurately classify lesions as benign or… Reference ID: 24-T-110 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Algorithm And System For Accurate Breast Parenchymal Enhancement Calculation By Digital Lesion Removal A method uses AI and clustering to remove lesions from breast MRI images, reconstructing clearer projection images for more accurate assessment of tissue enhancement… Interests: Imaging, Machine Learning/Artificial Intelligence Reference ID: 21-T-041 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Software AI Pipeline For Predicting Oral Cancer Progression An AI-driven system analyzes histopathology images of oral lesions using deep learning, self-supervised learning, and attention methods to predict cancer progression risk with explainable… Interests: Bioinformatics, Biomarker, Pathology, Point-of-Care Reference ID: 24-T-144 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Wearable Microelectromechanical Sensing System For Integrated Respiratory And Physiological Signal Monitoring A wearable, wireless sensor that integrates flexible, capacitive, acoustic, and optical technologies to continuously monitor breathing, heart signals, and oxygen levels for accurate sleep… Reference ID: 21-T-010 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Digital Proprioceptometer For Quantitatively Assessing Human Proprioceptive Performance The Unmet Need: Precise evaluation and effective treatment planning for proprioception Proprioception is a critical aspect of human motor control and balance, traditionally evaluated… Interests: Neurology Reference ID: 17-T-084 Desired Partnership: Co-development, Licensing IP: Patent Issued
