Materials Therapeutics Engineered Cardiac Microtissues Using Trace Silicon Nanowires To Improve Functional Maturity A trace amount of electrically conductive silicon nanowires (e-SiNWs) into otherwise scaffold-free hiPSC-derived cardiomyocyte spheroids to improve electrical coupling, synchronized beating, calcium handling, and… Interests: Cardiovascular Reference ID: 14-T-040
Therapeutics Novel RAD51 Inhibitors For Homologous Recombination Suppression And Chemosensitization A cell-active RAD51 inhibitor scaffold with an optimized reversible analog that reduces reactivity liabilities and is well suited for research-use commercialization and further oncology… Interests: Oncology, Oncology Radiotherapy Reference ID: 13-T-036
Diagnostics Therapeutics A Prognostic Signature For Breast Cancer This prognostic signature for breast cancer improves patient survival outcomes by assessing the coordinated regulation of HMGA2, TET1, and HOXA9 expression to guide targeted… Interests: Drug Screening, Oncology Reference ID: 13-T-081
Diagnostics Therapeutics c-CBL Mutations Predict Lung Cancer Sensitivity to Chemotherapeutic Agents that Target EGFR and MET A diagnostic technology that enables prediction of lung cancer sensitivity to targeted chemotherapeutic agents by identifying specific c-CBL gene mutations, thus facilitating more effective… Interests: Drug Screening, Oncology, Oncology Solid Tumor Reference ID: 10-T-070
Diagnostics Medical Devices AuNP-DG: Deoxyglucose Labeled Gold Nanoparticles as X-Ray Computed Tomography Contrast Agents for Cancer Imaging The targeted metabolic imaging enhancement achieved by deoxyglucose-labeled gold nanoparticles (AuNP-DG) offers superior tumor-specific contrast and improved resolution in computed tomography (CT) scans compared… Interests: Imaging, Imaging Agents, Oncology Radiotherapy, Oncology Solid Tumor Reference ID: 09-T-081
Diagnostics Research Tools A Versatile and High-throughput Assay for the Directed Evolution of Reverse Transcriptases to Profile Epigenetic Modifications With NGS Engineered reverse transcriptases (RTs) to profile epigenetic modifications have numerous advantages over traditional antibody enrichment methods including: single base pair resolution, lower sample quantities… Interests: Tangible Property Reference ID: 18-T-669 Desired Partnership: Licensing IP: Tangible property
Hardware Materials Nanopatterned Silicone Substrate for Stabilizing Chiral Hematic Liquid Crystals in Single Crystal Blue Phase Blue phase liquid crystalline structures are highly desirable for applications such as electro-optical devices (e.g. display screens) because of light reflection that includes wavelengths… Interests: Chemical Synthesis, Semiconductors Reference ID: 16-T-136 Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending
Research Tools Universal TaqMan-Based Detection System for RNA Quantification Reverse transcriptase quantitative PCR (qPCR) effectively quantifies coding and noncoding RNA expressions in cells and tissue samples. Among various RT-qPCR detection systems, SYBR Green-based… Reference ID: 22-T-196 Desired Partnership: Co-development, Licensing IP: Patent Pending
Hardware Quantum Sciences Tunable High-Q Superconducting mm-Wave Cavities Cavity and circuit quantum electrodynamics systems provide unprecedented control over photonic quantum states via coupling to strongly nonlinear single emitters. The millimeter (mm) wave… Interests: Computing Reference ID: 19-T-029 Desired Partnership: Co-development, Licensing IP: Patent Issued