Materials Stretchable Light-Emitting Polymers Electroluminescent (EL) devices represent one of the central components of multiple modern technologies. They offer unique functionality for information visualization, wireless signal/power transmission and… Interests: Electronic, Polymer Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Method To Use Low-Dose Tocilizumab To Treat Sickle Cell Disease Sickle cell disease (SCD) is a rare genetic disease that affects red blood cells, predominantly seen in African-American patients. Patients with SCD often have various… Interests: Drug Repurposing Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials Other Research Tools A New Method of Isotope Enrichment and Separation: Preferential Embedding of Heavier Isotopes Into Ices Isotope separation methods are key to numerous scientific and industrial processes. Nuclear power plants and weapons, for example, require fuels enriched in a select… Interests: Chemical Synthesis, Electronic, Medical Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Novel Delivery Platform For Controlled Release Of Bacterial Metabolites To Modulate The Immune System Conditioning of the immune system by the microbiome has received substantial attention for the scientific community in recent years. Microbial metabolites are being assessed… Interests: Drug Delivery, Wound Healing Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Small Molecule Immunopotentiator Conjugates of NF-KB Activators as Adjuvants With Enhanced Efficacy And Reduced Toxicity Imidazoquinolinone derivatives that activate Toll-like receptor (TLR) 7/8 are small molecule immune potentiators (SMIPs) that have potent activity as vaccine adjuvants and as anti-tumor… Interests: Oncology, Small Molecules, Vaccines Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Small Molecule Inhibitors Targeting RNA Modifying Enzymes to Modulate Drug Response and Overcome Drug Resistance DNA hypomethylating agents have been widely used to treat various hematologic and non-hematologic malignancies. However, accumulating evidence has demonstrated that DNA methylation status does… Interests: Drug Development Tool, Oncology, Small Molecules Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Machine Learning for Early Detection of Hypoxic‑Ischemic Brain Injury After Cardiac Arrest Despite the many advances in the field of resuscitation post cardiac arrest, hypoxic-ischemic brain injury (HIBI) leaves many survivors with severe neurological disability. Patients… Interests: Imaging, Imaging Agents, Machine Learning/Artificial Intelligence Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Antibody-Targeted Enzymatic Chemoprotection Cytotoxic chemotherapy involves drugs that inhibit cellular division, killing or blocking the growth of cancer cells. However, chemotherapy blocks the growth of noncancerous cells,… Interests: Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials A Controllable Synthesis Method Of Layered Oxides By Electrochemical Assisted Ion-Exchange Lithium-rich layered oxides are promising cathode materials with remarkable electrochemical performance that will revolutionize the electronics, transportation, battery, and grid energy storage industries. The… Interests: Chemical Synthesis, Electronic Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics SARS-CoV-2 Therapeutics Point Of Care Technology For SARS-CoV-2 Detection and Neutralization SARS-CoV-2’s enters cells when the receptor binding domain (RBD) of its spike protein (S-protein) interacts with angiotensin-converting enzyme 2 (ACE2). In order to block… Interests: Antibody, Antibody Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Anti-CD73(NT5E) Antibodies Specific To The Tumor Microenvironment CD73 is an ectonucleotidase tethered by a glycosylphosphatidyl anchor to the extracellular side of many cell types. Along with NTPDase-1 CD39, CD73 is an… Interests: Antibody, Oncology, Radiosensitizer Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Engineered Multipurpose Antibody Module Platform Traditionally, antibodies were produced using animal immunization methodologies.1 While this approach is still in broad use, recombinant display technologies have now assumed the leading… Interests: Antibody, Antibody, Drug Development Tool Desired Partnership: Co-development, Licensing IP: Patent Pending