Medical Devices Software DeMaND (Decoding using Manifold Neural Dynamics) This method enables high fidelity decoding of neural activity in an interpretable manner with a small training data set. The Unmet Need: Measuring neural… Interests: Neurology Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices Research Tools New Toolkit And Methods For Large-Scale Spatial Transcriptomics Tools and methods to map the entire transcriptome with large-scale histology sections from whole animal or whole human organs with high resolution and sensitivity… Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Chimeric Antigen Coreceptor System For Optimized Antigen Targeting A novel chimeric antigen coreceptor system mimicking the CD4/CD8 and TCR interaction to enhance signaling for increased antigen sensitivity to treat B cell malignancies.… Interests: Immunotherapy, Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Point Of Care Monitoring Of Inflammatory Diseases A quantitative method of calprotectin measurement from various biological samples to monitor disease severity, progression, and effectiveness of treatment interventions in inflammatory diseases. The… Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Antibody Blockade Method To Augment Hemolysis For Treatment Of Sepsis Sepsis is a systemic response to infection and remains a leading cause of death in intensive care units worldwide while our understanding of the… Interests: Microbiology/Virology Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Programmable And Hyperstable Engineered Synthetic Transcriptional Repressors A class of functionally enhanced synthetic transcriptional factor antagonists to modulate the MYC/MAX transcriptional network by direct competition for DNA binding. The Unmet Need:… Interests: New Chemical Entity, Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Novel In Vivo Gene Editing System A engineered OgeuIscB- ωRNA for efficient and precise genome editing with increased potency and specificity while more compact in size compared to other CRISPR-Cas… Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Diagnostic For Predicting Hospital-Acquired Infections And Identifying Causative Organisms The technology is a fecal microbiome metabolite profile that can predict hospital-acquired infections and identify the causative organisms. This method efficiently measures specific chemical… Interests: Biomarker Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Genetic Engineering Tools To Stimulate And Enhance The Production Of Select Compounds From Bacterial Species Synthetic biology toolsets to genetically manipulate the microbiota, specifically non-model resident gut microbes, to alter gene expression and cellular function to produce therapeutic compounds.… Interests: Gastrointestinal, Immunology, Inflammatory, Metabolic Disorders, Microbiome Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Microbiome-Based Therapeutic For Enhancing Anti-Tumor Immunity In Cancer Treatment Innovative therapeutic strategy leveraging commensal microbiota, specifically by oral administration of Bifidobacterium, to enhance anti-tumor immunity, potentially improving cancer treatment when combined with checkpoint… Interests: Biologics, Combination Therapy, Immunotherapy, Microbiome, Oncology, Oncology Hematopoietic, Oncology Solid Tumor Desired Partnership: Co-development, Licensing IP: Patent Issued
Hardware Quantum Sciences Low-loss Niobium Josephson Junctions That Improve Quantum Device Performance SUMMARY The invention introduces a method for fabricating low-loss niobium Josephson junctions which enhance quantum device performance by using niobium superconductors that are separated… Interests: Computing Desired Partnership: Co-development, Licensing IP: PCT Pending
Therapeutics Prophylactic Strategy For C. Difficile Infection Prevention This technology is a prevention method for those at risk of C. difficile infection using a mutated strain of C. difficile that reduces toxicity… Interests: Gastrointestinal, Infectious Disease, Microbiome, Vaccines Desired Partnership: Co-development, Licensing IP: Patent Pending
