Therapeutics RNA-Guided Control Of Protein Secretion And Membrane Protein Expression Innovative methods to engineer small nucleolar RNAs to target specific mRNAs to increase or decrease the secretion of desired proteins offering scalable solutions for… Reference ID: 24-T-115 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Targeting the BRCA1 Pseudogene (BRCA1P1) to Inhibit Cancer Progression and Increase Therapy Responses Compositions and methods to target long non-coding RNA (lncRNA) from the BRCA1 pseudogene in breast cancer cells to stimulate the body’s natural immune response,… Interests: Oncology Reference ID: 22-T-092 Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices Software DeMaND (Decoding using Manifold Neural Dynamics) This method enables high fidelity decoding of neural activity in an interpretable manner with a small training data set. The Unmet Need: Measuring neural… Interests: Neurology Reference ID: 23-T-075 Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices Research Tools New Toolkit And Methods For Large-Scale Spatial Transcriptomics Tools and methods to map the entire transcriptome with large-scale histology sections from whole animal or whole human organs with high resolution and sensitivity… Reference ID: 22-T-069 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Chimeric Antigen Coreceptor System For Optimized Antigen Targeting A novel chimeric antigen coreceptor system mimicking the CD4/CD8 and TCR interaction to enhance signaling for increased antigen sensitivity to treat B cell malignancies.… Interests: Immunotherapy, Oncology Reference ID: 24-T-042 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Point Of Care Monitoring Of Inflammatory Diseases A quantitative method of calprotectin measurement from various biological samples to monitor disease severity, progression, and effectiveness of treatment interventions in inflammatory diseases. The… Reference ID: 24-T-081 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Antibody Blockade Method To Augment Hemolysis For Treatment Of Sepsis Sepsis is a systemic response to infection and remains a leading cause of death in intensive care units worldwide while our understanding of the… Interests: Microbiology/Virology Reference ID: 23-T-108 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Programmable And Hyperstable Engineered Synthetic Transcriptional Repressors A class of functionally enhanced synthetic transcriptional factor antagonists to modulate the MYC/MAX transcriptional network by direct competition for DNA binding. The Unmet Need:… Interests: New Chemical Entity, Oncology Reference ID: 21-T-006 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Novel In Vivo Gene Editing System A engineered OgeuIscB- ωRNA for efficient and precise genome editing with increased potency and specificity while more compact in size compared to other CRISPR-Cas… Reference ID: 23-T-121 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Diagnostic For Predicting Hospital-Acquired Infections And Identifying Causative Organisms The technology is a fecal microbiome metabolite profile that can predict hospital-acquired infections and identify the causative organisms. This method efficiently measures specific chemical… Interests: Biomarker Reference ID: 23-T-027 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Genetic Engineering Tools To Stimulate And Enhance The Production Of Select Compounds From Bacterial Species Synthetic biology toolsets to genetically manipulate the microbiota, specifically non-model resident gut microbes, to alter gene expression and cellular function to produce therapeutic compounds.… Interests: Gastrointestinal, Immunology, Inflammatory, Metabolic Disorders, Microbiome Reference ID: 23-T-162 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Microbiome-Based Therapeutic For Enhancing Anti-Tumor Immunity In Cancer Treatment Innovative therapeutic strategy leveraging commensal microbiota, specifically by oral administration of Bifidobacterium, to enhance anti-tumor immunity, potentially improving cancer treatment when combined with checkpoint… Interests: Biologics, Combination Therapy, Immunotherapy, Microbiome, Oncology, Oncology Hematopoietic, Oncology Solid Tumor Reference ID: 14-T-105 Desired Partnership: Co-development, Licensing IP: Patent Issued
