Diagnostics Research Tools Therapeutics An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV… Interests: Gene Therapy, Genomics Reference ID: 23-T-046 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics A Transcriptomic Signature Platform For Predicting Prognosis And Guiding Therapy In Ovarian Cancer Patients A 10-gene signature based on glucocorticoid receptor activity to predict survival risk in high-grade serous ovarian cancer patients, helping identify those who may benefit… Interests: Biomarker Reference ID: 26-T-022 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Glycan Proximity Sequencing (GPS) For Single-Cell Multi-omics Glycoproteomics TL;DR: Glycan Proximity Sequencing (GPS) is a next-generation single-cell multi-omics assay that measures mRNA expression, extracellular protein abundance, global glycan motifs, and protein-specific glycoforms… Interests: Biomarker Reference ID: 26-T-004 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Therapeutics New Reversible Uridine Modification Chemistry For Labeling and Functionalizing Native Nucleic Acids A chemical process that enables reversible, covalent RNA modification-highly selective for uridine enabling diverse functional group attachment, facilitating nucleic acid labeling The Unmet Need:… Interests: Bioinformatics, Biologics, Biomarker, Chemical Synthesis, Chemical Synthesis, Drug Delivery, Genomics, Imaging Agents, Medical, New Chemical Entity, Sequencing Reference ID: 25-T-126 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics Prolactin Receptor Antibodies For Targeted Cancer Therapy And Diagnosis Novel antibodies precisely targeting cancer cells by binding to the Prolactin Receptor (PRLR) to diagnose cancer, direct immune cells to destroy tumors, and inhibit… Interests: Antibody, Oncology Reference ID: 25-T-104 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools A High-Throughput, Label-Free Microfluidic System For Combinatorial Droplet Generation, Storage, And Analysis A microfluidic platform consisting of a two-layer PDMS system that generates and stores combinatorial droplets, enabling high-throughput screening with an integrated label-free, image-based detection… Reference ID: 25-T-014 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Low-Input Methylation Sequencing For Profiling Epitranscriptomic Signatures And Early Colorectal Cancer Diagnosis A method that analyzes cfRNA methylation in plasma to distinguish human RNA from microbiome RNA, accurately detecting colorectal cancer through specific methylation markers even… Interests: Epigenetics, Microbiology/Virology, Sequencing Reference ID: 24-T-187 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Computerized Adaptive Testing System For Real-Time Multidimensional Fatigability Assessment A computerized adaptive test using a bifactor model on tablet devices to measure fatigue relative to activity delivering personalized, real-time insights by integrating with… Reference ID: 25-T-089 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Software Computational Framework For Unraveling Single-Cell Transcriptional Dynamics Novel system using statistical topic modeling and a bursty transcriptional model to analyze spliced and unspliced RNA, revealing precise cell state transitions and dynamics… Reference ID: 22-T-208 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Software AI Pipeline For Predicting Oral Cancer Progression An AI-driven system analyzes histopathology images of oral lesions using deep learning, self-supervised learning, and attention methods to predict cancer progression risk with explainable… Interests: Bioinformatics, Biomarker, Pathology, Point-of-Care Reference ID: 24-T-144 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Algorithm And System For Accurate Breast Parenchymal Enhancement Calculation By Digital Lesion Removal A method uses AI and clustering to remove lesions from breast MRI images, reconstructing clearer projection images for more accurate assessment of tissue enhancement… Interests: Imaging, Machine Learning/Artificial Intelligence Reference ID: 21-T-041 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Digital Proprioceptometer For Quantitatively Assessing Human Proprioceptive Performance The Unmet Need: Precise evaluation and effective treatment planning for proprioception Proprioception is a critical aspect of human motor control and balance, traditionally evaluated… Interests: Neurology Reference ID: 17-T-084 Desired Partnership: Co-development, Licensing IP: Patent Issued
