Therapeutics siRNA/shRNA Therapy for the Sensitization of Treatment-resistant Solid Tumors to Chemo and Radiation Therapy Adjuvant radiation therapy post-surgery remains largely ineffective, with just 5% of patients showing a survival benefit. Small molecule JAK inhibitors have shown efficacy in… Interests: Oncology, Oncology Hematopoietic, Oncology Radiotherapy, Oncology Solid Tumor Reference ID: 12-T-099 Desired Partnership: Co-development, Licensing IP: Patent Issued
Therapeutics Novel Small Molecule Treatment for Staphylococcus Aureus SSTI Infections SUMMARY Staphylococcus aureus infects 50,000 patients and kills 20,000 annually in the United States alone. With widespread antibiotic resistance, there is an urgent need… Interests: Antibody, Biologics, Drug Screening, Infectious Disease Reference ID: 10-T-108 Desired Partnership: Co-development, Licensing IP: Patent Issued
Diagnostics Therapeutics IRDS: Predictive 7-gene Signature for Breast Cancer Therapy After surgical removal of breast cancer tumors, adjuvant chemotherapy and radiation therapy have an absolute survival benefit of just 5-10%. Currently approved breast cancer… Reference ID: 05-T-101 Desired Partnership: Licensing IP: Patent Issued
Therapeutics A Potent Glioma Targeting CAR T-Cell With Minimal Off-Target Toxicity IL13Ra2 is a cancer testis antigen that is expressed in 50-80% of glioblastoma cells, has no basal expression in the healthy tissue, and is… Interests: Biologics, Oncology Solid Tumor Reference ID: 15-T-006 Desired Partnership: Licensing IP: Patent Issued
Therapeutics A Low Dose, Multi-drug Cocktail for the Treatment of Metastatic and Resistant Breast Cancers An estimated 20-30% of breast cancer patients suffer from metastatic recurrence, which can be perpetuated by an overreliance on high doses of a single… Interests: Combination Therapy, Oncology, Oncology Solid Tumor Reference ID: 18-T-043 Desired Partnership: Co-development, Licensing IP: Patent Pending
Other Method for the in Vitro Generation of Trabecular Bone Trabecular (Cancellous) bone is a porous bone found in the spine and hip and is desirable for bone grafting because of its osteogenic properties.… Interests: Biologics, Cell Line, Drug Screening, Musculoskeletal Reference ID: 15-T-107 Desired Partnership: Co-development, Licensing IP: Patent Pending
Software Human Brain-Inspired Algorithm for Neural Network “Memory” Catastrophic forgetting or interference is the inability of an artificial neural network (ANN) to learn multiple sequential tasks without a degradation in the accuracy… Interests: Machine Learning/Artificial Intelligence Reference ID: 18-T-086 Desired Partnership: Co-development, Investment, Licensing IP: Patent Issued
Diagnostics Therapeutics Neurophysiological Biomarker for Early ALS Detection Presently, physicians rely on a costly and invasive battery of tests for diagnosing ALS. Early detection of ALS can improve patient survival and quality… Interests: Healthcare IT, Neurology Reference ID: 18-T-074 Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending
Diagnostics Patient Microbiota As A Predictive Biomarkers For Response To Checkpoint Blockade Therapy Improved prediction of patient response to checkpoint blockade immunotherapy through identification of specific gut microbiota biomarkers, thereby enhancing clinical decision-making and treatment efficacy in… Interests: Biomarker Reference ID: 17-T-051
Materials Therapeutics Engineered Cardiac Microtissues Using Trace Silicon Nanowires To Improve Functional Maturity A trace amount of electrically conductive silicon nanowires (e-SiNWs) into otherwise scaffold-free hiPSC-derived cardiomyocyte spheroids to improve electrical coupling, synchronized beating, calcium handling, and… Interests: Cardiovascular Reference ID: 14-T-040
Therapeutics Novel RAD51 Inhibitors For Homologous Recombination Suppression And Chemosensitization A cell-active RAD51 inhibitor scaffold with an optimized reversible analog that reduces reactivity liabilities and is well suited for research-use commercialization and further oncology… Interests: Oncology, Oncology Radiotherapy Reference ID: 13-T-036
Diagnostics Therapeutics A Prognostic Signature For Breast Cancer This prognostic signature for breast cancer improves patient survival outcomes by assessing the coordinated regulation of HMGA2, TET1, and HOXA9 expression to guide targeted… Interests: Drug Screening, Oncology Reference ID: 13-T-081
