Diagnostics Research Tools SARS-CoV-2 Machine Learning-Based Prediction Of Viral Mutations From Genomic Sequences Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Bioinformatics, Bioinformatics, Machine Learning/Artificial Intelligence Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics SARS-CoV-2 Therapeutics SARS-CoV-2 Monoclonal Antibodies Against Spike and Internal Proteins for Therapeutics and Diagnostics As of February 2021, there have been over 107 million cases and over 2 million deaths caused worldwide by the novel virus SARS-CoV-2. Few… Interests: Antibody, Antibody, Microbiology/Virology Desired Partnership: Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics A Platform for Developing High-Affinity Selective Binding Proteins to Short and Flexible Peptide Motifs Short and flexible peptide motifs such as GPCRs and histone tails are attractive targets for therapeutic development, but the generation of traditional antibodies against… Desired Partnership: Licensing IP: Patent Pending
Diagnostics Therapeutics Peripheral Blood-Based Proteinomic Test for The Diagnosis of Idiopathic Pulmonary Fibrosis (IPF) The current clinical standards for diagnosing idiopathic pulmonary fibrosis (IPF) include lung biopsies and radiographic examination, which cannot reliably discriminate between IPF patients and… Interests: Biomarker Desired Partnership: Licensing IP: Patent Issued
Diagnostics Medical Devices Therapeutics A High Throughput Microfluidic Chip With Precise Environmental Control for Cell and Organoid Culture Microfluidic chips are useful in applications such as drug discovery assays because of their ability to replicate dynamic cellular environments in a high-throughput and… Desired Partnership: Licensing IP: Patent Pending
Diagnostics Software Therapeutics Clinical Risk Stratification (CRS) for Colorectal Cancer Metastases Metastases are the leading cause of death in solid state tumor patients and as such are commonly viewed as widespread and incurable. Despite this,… Interests: Oncology Desired Partnership: Licensing IP: Patent Pending
Diagnostics Therapeutics IRDS: Predictive 7-gene Signature for Breast Cancer Therapy After surgical removal of breast cancer tumors, adjuvant chemotherapy and radiation therapy have an absolute survival benefit of just 5-10%. Currently approved breast cancer… Desired Partnership: Licensing IP: Patent Issued
Diagnostics Therapeutics A Prognostic Gene Signature for Predicting Chemotherapy Sensitivity and Patient Survival in ER-negative Breast Cancer ER-negative (ER-) breast cancers make up 20% of all breast cancer diagnosis. However, no gene signature exists for predicting drug sensitivity and prognosis. Therefore,… Interests: Oncology, Oncology Solid Tumor Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Therapeutics Genetic Signature to Predict NAC Efficacy in Treating Idiopathic Pulmonary Fibrosis (IPF) N-Acetylcysteine (NAC) is commonly used to break down mucous and lessen lung function decline but has traditionally shown low efficacy in treating patients with… Interests: Genomics Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Therapeutics Neurophysiological Biomarker for Early ALS Detection Presently, physicians rely on a costly and invasive battery of tests for diagnosing ALS. Early detection of ALS can improve patient survival and quality… Interests: Healthcare IT, Neurology Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending
Diagnostics Research Tools A Versatile and High-throughput Assay for the Directed Evolution of Reverse Transcriptases to Profile Epigenetic Modifications With NGS Engineered reverse transcriptases (RTs) to profile epigenetic modifications have numerous advantages over traditional antibody enrichment methods including: single base pair resolution, lower sample quantities… Interests: Tangible Property Desired Partnership: Licensing IP: Tangible property