Diagnostics Therapeutics Identification of Structurally Novel BTK Mutations That Drive Resistance to BTK Inhibitors in CLL and Non-Hodgkin Lymphomas Non-Hodgkin’s lymphoma is among the most common types of cancer in the US consisting of a diverse group of lymphocytic malignancies. Most of these… Interests: Oncology, Oncology Hematopoietic, Point-of-Care Reference ID: 16-T-041 Desired Partnership: Co-development, Licensing IP: Patent Issued
Diagnostics Software A System for Frailty Assessment, Frailty Mitigation, and Clinical Research Frailty is a condition that often affects the elderly. It is characterized by increased susceptibility to physiologic stressors such as illness and major surgery.… Interests: Healthcare IT, Musculoskeletal Reference ID: 21-T-046 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Software Automatic Prediction of Cancer Recurrence through Machine Learning Deep learning tools are becoming increasingly popular for histologic analyses and have been used to predict tumor biomarker status, clinical variables, tumor subtypes, and… Interests: Machine Learning/Artificial Intelligence, Pathology Reference ID: 21-T-118 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics Next-Generation Activity-Based Radiotracer For In Vivo Positron Emission Tomography (PET) Imaging And Therapy Cancer cells show alterations in metabolism that support malignancy and disease progression. Prominent among these metabolic changes is elevations in neutral ether lipids (NELs).… Interests: Imaging Agents, Small Molecules Reference ID: 20-T-023 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools SARS-CoV-2 Machine Learning-Based Prediction Of Viral Mutations From Genomic Sequences There have been significant research efforts to develop machine learning and predictive analytics based tools to predict viral evolution which remains the main obstacle… Interests: Bioinformatics, Bioinformatics, Machine Learning/Artificial Intelligence Reference ID: 21-T-011 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices PET Detector Systems Employing Ionization-Activated Organic Fluors An advanced Positron Emission Tomography (PET) detector system that achieves lower radiation dose and higher spatial and temporal resolution by utilizing ionization-activated organic fluor… Interests: Imaging Reference ID: 21-T-019
Diagnostics SARS-CoV-2 Therapeutics SARS-CoV-2 Monoclonal Antibodies Against Spike and Internal Proteins for Therapeutics and Diagnostics As of February 2021, there have been over 107 million cases and over 2 million deaths caused worldwide by the novel virus SARS-CoV-2. Few… Interests: Antibody, Antibody, Microbiology/Virology Reference ID: 21-T-040 Desired Partnership: Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics A Platform for Developing High-Affinity Selective Binding Proteins to Short and Flexible Peptide Motifs Short and flexible peptide motifs such as GPCRs and histone tails are attractive targets for therapeutic development, but the generation of traditional antibodies against… Reference ID: 06-T-018 Desired Partnership: Licensing IP: Patent Pending
Diagnostics Therapeutics Peripheral Blood-Based Proteinomic Test for The Diagnosis of Idiopathic Pulmonary Fibrosis (IPF) The current clinical standards for diagnosing idiopathic pulmonary fibrosis (IPF) include lung biopsies and radiographic examination, which cannot reliably discriminate between IPF patients and… Interests: Biomarker Reference ID: 11-T-031 Desired Partnership: Licensing IP: Patent Issued
Diagnostics Medical Devices Therapeutics A High Throughput Microfluidic Chip With Precise Environmental Control for Cell and Organoid Culture Microfluidic chips are useful in applications such as drug discovery assays because of their ability to replicate dynamic cellular environments in a high-throughput and… Reference ID: 16-T-109 Desired Partnership: Licensing IP: Patent Pending
Diagnostics Therapeutics IRDS: Predictive 7-gene Signature for Breast Cancer Therapy After surgical removal of breast cancer tumors, adjuvant chemotherapy and radiation therapy have an absolute survival benefit of just 5-10%. Currently approved breast cancer… Reference ID: 05-T-101 Desired Partnership: Licensing IP: Patent Issued
Diagnostics Therapeutics A Prognostic Gene Signature for Predicting Chemotherapy Sensitivity and Patient Survival in ER-negative Breast Cancer ER-negative (ER-) breast cancers make up 20% of all breast cancer diagnosis. However, no gene signature exists for predicting drug sensitivity and prognosis. Therefore,… Interests: Oncology, Oncology Solid Tumor Reference ID: 17-T-011 Desired Partnership: Co-development, Licensing IP: Patent Pending
