Materials Research Tools Therapeutics Scalable Bioelectronic Production Of Extracellular Vesicles For Regenerative Medicine Bioelectronic devices and methods for the electrical stimulation of cells and engineered tissue for the scalable production of extracellular vesicles for drug delivery and… Interests: Medical, Stem Cell Therapy Reference ID: 23-T-048 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Programmed RNA Editing with an Evolved Bacterial Adenosine Deaminase A novel platform, bacterial deaminase-enabled recoding of RNA (DECOR), utilizing an engineered bacterial adenosine deaminase to achieve programmable adenosine-to-inosine (A-to-I) editing on single-stranded RNA.… Interests: Gene Therapy Reference ID: 24-T-189 Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices Research Tools New Toolkit And Methods For Large-Scale Spatial Transcriptomics Tools and methods to map the entire transcriptome with large-scale histology sections from whole animal or whole human organs with high resolution and sensitivity… Reference ID: 22-T-069 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Novel In Vivo Gene Editing System A engineered OgeuIscB- ωRNA for efficient and precise genome editing with increased potency and specificity while more compact in size compared to other CRISPR-Cas… Reference ID: 23-T-121 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Genetic Engineering Tools To Stimulate And Enhance The Production Of Select Compounds From Bacterial Species Synthetic biology toolsets to genetically manipulate the microbiota, specifically non-model resident gut microbes, to alter gene expression and cellular function to produce therapeutic compounds.… Interests: Gastrointestinal, Immunology, Inflammatory, Metabolic Disorders, Microbiome Reference ID: 23-T-162 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Exploiting Chromosomal Passenger Complex (CPC) Proteins For Immunotherapeutic Applications Cell division is a fundamental biological process, ensured to be of high fidelity by the Chromosome Passenger Complex (CPC), a crucial protein complex involved… Interests: Antibody, Antibody Reference ID: 22-T-035 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Optogenetic Protein Fusion for Precise And Low-Impact Actin Cytoskeleton Imaging In Cells A light-sensitive version of LifeAct, a peptide used to label actin in cells, to reduce its harmful side effects by controlling its binding through… Interests: Imaging Reference ID: 21-T-126 Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials Other Research Tools A New Method of Isotope Enrichment and Separation: Preferential Embedding of Heavier Isotopes Into Ices Isotope separation methods are key to numerous scientific and industrial processes. Nuclear power plants and weapons, for example, require fuels enriched in a select… Interests: Chemical Synthesis, Electronic, Medical Reference ID: 21-T-042 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools SARS-CoV-2 Therapeutics Neutralizing Monoclonal Antibodies Against SARS-CoV-2 The landscape of SARS-CoV-2 is experiencing a novel development of viral variants harboring mutations that can escape even the most highly potent antibodies against… Interests: Antibody, Antibody Reference ID: 22-T-070 Desired Partnership: Co-development, Licensing IP: Patent Pending
Quantum Sciences Research Tools Software Computational-Guided Spin Defect Systems This method enables predictive growth of qubit host materials without the limitations of iterative measurements. The Unmet Need: Proper characterization of qubit host substrate… Interests: Electronic Reference ID: 23-T-065 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics Next-Generation Activity-Based Radiotracer For In Vivo Positron Emission Tomography (PET) Imaging And Therapy Cancer cells show alterations in metabolism that support malignancy and disease progression. Prominent among these metabolic changes is elevations in neutral ether lipids (NELs).… Interests: Imaging Agents, Small Molecules Reference ID: 20-T-023 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Novel Mycobacterial Small Molecules That Bind MR1 And Are Activating Or Antagonistic For MR1-Restricted T cells. TB bacterium, Mycobacterium tuberculosis (M. tuberculosis), is extremely slow growing compared to other bacteria and is naturally resistant to many of the powerful antibiotics… Interests: Drug Screening, Infectious Disease, Small Molecules Reference ID: 16-T-125 Desired Partnership: Co-development, Licensing IP: Patent Pending
