Therapeutics Novel RNA Replicon Vector For Efficient Gene Delivery To The Skin Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Dermatology, Rare/Orphan Diseases Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Small Molecule Splicing Modulators For Reducing Aggregatable Prion Protein In Prion Diseases First-in-class small molecules to change how the PRNP gene is spliced, reducing harmful prion levels and offering a new treatment approach for prion diseases… Interests: Neurology, Rare/Orphan Diseases, Small Molecules Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV… Interests: Gene Therapy, Genomics Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials SARS-CoV-2 Therapeutics A Next-Generation mRNA Vaccine Platform For Enhancing T-Cell Responses And Improving Antiviral And Antitumor Immunity Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Biologics, Drug Delivery, Immunology, Immunotherapy, Microbiology/Virology, Oncology, Polymer, Vaccines Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Computational And Therapeutic Platform For Identifying And Correcting Unproductive Splicing To Restore Gene Expression Advanced computational tools to identify faulty RNA splicing events and design of antisense oligonucleotides to restore normal protein production in genetic diseases, especially those… Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC… Interests: Drug Development Tool, Drug Screening, Drug Target, Oncology Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics A Transcriptomic Signature Platform For Predicting Prognosis And Guiding Therapy In Ovarian Cancer Patients Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Biomarker Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Glycan Proximity Sequencing (GPS) For Single-Cell Multi-omics Glycoproteomics Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Biomarker Desired Partnership: Co-development, Licensing IP: Patent Pending
Technology Classifications Therapeutics Topical Vitamin B1-Based Immunomodulation For Enhancing Skin Wound Healing And Anti-Tumor Responses Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Oncology, Wound Healing Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics PMO-Based RNA-Degrading Chimeras For Targeted Degradation Of α-Synuclein mRNA In Neurodegenerative Diseases Phosphorodiamidate morpholino oligomer (PMO)-based RNA-degrading chimeras reduce α-synuclein protein by degrading its messenger RNA preventing protein aggregation and propagation associated with neurodegenerative diseases. The… Interests: Biologics, Drug Development Tool, Neurology, Rare/Orphan Diseases Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Next-Generation Immunotherapy Platform With Engineered Collagen-Binding Cytokine Combinations Combination engineered IL-7 and IL-12 proteins that target tumors by binding to collagen, boosting immune attack on cancer while reducing side effects and improving… Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States,… Interests: Biomarker, Drug Target, Oncology, Oncology Hematopoietic Desired Partnership: Co-development, Licensing IP: Patent Pending
