SUMMARY Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States, there are 1.1 million burn injuries which require medical attention each year. These injuries often result in significant scarring having a negative impact on the… Read More
SUMMARY Cardiac catherization, or angiography, is a procedure used to gain access to a patient's arterial system, and is used to treat and diagnose many heart conditions. While the transfermoral (through groin) approach has been more prevalent, the transradial (through wrist) approach (TRA) is gaining popularity due to lower complication… Read More
SUMMARY Post-CPR cardiogenic shock is associated with hemodynamic instability and poor neurological outcomes. The pathophysiology is unknown and current treatment approaches merely restore basal cardiac function and do not protect against longer term damage. The inventors demonstrated that the main mechanism leading to post-CPR cardiogenic shock is myocardial stunning, which… Read More
SUMMARY Silicon is highly desirable for biomedical device applications because of its thermal and mechanical properties, as well as its biocompatibility. However, its practical application is presently limited by a lack of deformability and degradability. The inventors developed a novel amorphous silicon material that retains all the advantageous properties of… Read More
SUMMARY Electric organ stimulation has shown promise in the clinic for treating aberrant neurological and cardiac activity. Problematically, this approach is limited by the high risk associated with surgical or gene editing approaches to implant these stimulation systems. The inventors engineered a specifically doped silicone wire network on a flexible… Read More
SUMMARY Abnormal myocardial oxygen usage can predict heart attack or heart transplant rejection before the onset of clinical symptoms. However, there are currently no robust and reliable methods for globally measuring myocardial oxygen use and tissue strain despite the capability of this diagnostic tool to offer patients earlier access to… Read More