Therapeutics Novel Exosome-Based Drug Delivery For Targeting Alzheimer’s Disease and Cognitive Decline A novel drug delivery system using exosomes derived from hippocampus neuron cells engineered to express the Fe65 protein targeting amyloid-β precursor protein to reduce… Interests: Drug Delivery, Neurology Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Fully Synthetic Adjuvant Delivery System For Enhanced Tumor-Targeted Immunotherapy A cancer vaccine that enhances immune response by directly binding adjuvants to tumor cells, avoiding targeting antibodies, and reducing related side effects The problem:… Interests: Oncology, Vaccines Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics RNA Editing Technology for Enhancing Tumor Immunogenicity and Immune Checkpoint Inhibitors Novel RNA editing method to generate a multitude of neoantigens in tumor cells making the cells more recognizable by T cells and enhancing the… Interests: Immunooncology, Oncology, Oncology Solid Tumor Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Novel Metabolite-Based Diagnostic Technology for Accurate Cavernous Angioma Identification and Risk Assessment Newly identified plasma metabolites linked to cavernous angioma, a neurovascular disease, using machine learning and multi-omics data to improve diagnostic precision and offer new… Interests: Biomarker Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Targeting TGFβ Signaling for Enhancing Cancer Radiotherapy and Immunotherapy Efficacy The method leverages a negative regulator to inhibit TGFβ signaling in myeloid cells, potentially enhancing the efficacy of radiotherapy and immunotherapy in cancer treatment… Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Exploiting Chromosomal Passenger Complex (CPC) Proteins For Immunotherapeutic Applications Cell division is a fundamental biological process, ensured to be of high fidelity by the Chromosome Passenger Complex (CPC), a crucial protein complex involved… Interests: Antibody, Antibody Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Protein Engineering Strategy for Enhancing Healing Of Chronic Diabetic and Radiation-Induced Wounds The problem: Chronic, non‐healing wounds have reached epidemic proportions and have a sustainable impact on both an individual’s quality of life and on healthcare… Interests: Wound Healing Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Boosting Cancer Immunotherapy Or Radio-Immunotherapy For Enhanced Tumor Eradication New cancer therapy to enhance the efficacy of checkpoint inhibitor immunotherapy and radiation by blocking tumor-promoting signals from erythroid progenitor cells, which secrete artemin… Interests: Immunotherapy, Oncology, Oncology Radiotherapy Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Viral RNA Modification Technique To Create Attenuated Live Vaccines For Respiratory Syncytial Virus (RSV) and Other NNS RNA Viruses A method to attenuate RSV and other NNS RNA viruses by reducing m6A modifications on their RNA. This approach enhances genetic stability, ensures sufficient… Interests: Vaccines Desired Partnership: Co-development, Licensing IP: Patent Issued
Therapeutics A Targeted Radiopharmaceutical Platform For Improving Diagnosis And Treatment Of Neuroendocrine Tumors Advanced imaging and targeted radiotherapy for neuroendocrine tumors, using DOTATATE-based agents for precise diagnosis and treatment, and enhancing therapy effectiveness by adding Fulvestrant as… Interests: Oncology, Oncology Radiotherapy Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics COMT inhibitors for impulsive behaviors Drug repurposing to use catechol-O-methyl-transferase inhibitors for treating impulse control disorders, obsessive-compulsive disorders, and substance addictions The Unmet Need: New options for treating impulsive… Interests: Neurology Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Optogenetic Protein Fusion for Precise And Low-Impact Actin Cytoskeleton Imaging In Cells A light-sensitive version of LifeAct, a peptide used to label actin in cells, to reduce its harmful side effects by controlling its binding through… Interests: Imaging Desired Partnership: Co-development, Licensing IP: Patent Pending
