Therapeutics Tolerizing Agonist/Immunomodulator Loaded Liposomes for Long-Lived Immune Tolerance A failure of central immune tolerance typically driven by autoantigen specific T regulatory (Treg) cells is the primary cause of many autoimmune diseases. This… Interests: Autoimmune, Transplantation Reference ID: 22-T-003 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools OSCA: A System For Efficient Construction Of Adenovirus Vectors Adenoviruses (Ad) are a non-enveloped linear double-stranded DNA viruses with over 50 serotypes identified in humans. They have received significant attention as an in… Interests: Drug Delivery, Drug Development Tool Reference ID: 21-T-143 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Software SCALES: A System For Predicting Interaction And Function In Bacteria Using Co-Variation The current understanding of how proteins interact to create collective functional groups (e.g., complexes, pathways, meta-pathways) is incomplete and difficult to elucidate. Therefore, the… Interests: Microbiology/Virology Reference ID: 21-T-093 Desired Partnership: Co-development, Licensing IP: Patent Pending
SARS-CoV-2 Therapeutics Drug Repurposing To Inhibit Nsp15 Endoribonuclease/NendU From SARS-CoV-2 There have been significant research efforts to develop various COVID-19 treatments. Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus… Interests: Infectious Disease, Small Molecules Reference ID: 20-T-062 Desired Partnership: Co-development, Licensing IP: Patent Issued
Materials Sulfur-Containing Organic-Inorganic Hybrid Materials Organic‐inorganic hybrid sulfur‐containing materials show promising properties for a variety of applications (e.g., superconductors, thermoelectrics, etc.). Efficient synthesis of such compounds—especially those containing dithiolene‐type… Interests: Chemical Synthesis Reference ID: 19-T-107 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Nanomaterial Based Intracellular Drug Delivery Of Therapeutic Peptides Intracellular delivery involves introduction of small biomolecules, nucleic acids, proteins, synthetic nanomaterials and drugs into the cell. There is a lot of focus on… Interests: Biologics, Drug Delivery Reference ID: 21-T-027 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Development Of A Novel Anti-fibrotic (siRNA Talin2) That Reverses Existing Fibrosis Fibrosis is involved in 45% of deaths in the United States, and no treatment exists to reverse the progression of the disease. Fibrosing diseases… Interests: Autoimmune, Drug Target, Inflammatory Reference ID: 21-T-091 Desired Partnership: Co-development, Licensing IP: Patent Pending
Cleantech Materials Functionalized Molybdenum Disulfide Membranes For Water Filtration The invention is a method to fabricate membranes made from exfoliated molybdenum disulfide (MoS2) for improved separation performance and membrane stability. Reverse osmosis (RO)… Interests: Chemical Synthesis Reference ID: 20-T-058 Desired Partnership: Co-development, Licensing IP: Patent Pending
Cleantech Materials A Biodegradable Packaging Material Made From Hybrid Hydrogel of Starch, Granular, Chitosan Fiber, and Polyacrylamide Starch and chitosan are abundant, natural, complex polysaccharides. In plants, starch is the carbohydrate energy reserve. Chitosan is the de-acetylated form of chitin, a… Interests: Chemical Synthesis, Composite Reference ID: 19-T-152 Desired Partnership: Co-development, Licensing IP: Patent Pending
Cleantech Hardware Materials Improved Photovoltaic Materials Based on Alpha-Substituted Perylene Diimide Use of organic photovoltaic (OPV) solar cells are a developing energy technology which shows significant potential to become a cheap source of electric energy… Reference ID: 15-T-132 Desired Partnership: Co-development, Licensing IP: Patent Pending
SARS-CoV-2 Therapeutics Hydrocarbon-Stapled Peptides To Inhibit SARS-CoV-2 Viral Infection The SARS-CoV-2 virus spreads by binding its spike protein to the human angiotensin-converting enzyme 2 (hACE2) protein expressed at the cell surface of lungs,… Interests: Infectious Disease Reference ID: 21-T-050 Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials Functionalized Metal Carbides For Energy Storage The invention is a novel synthetic approach for surface modification of two-dimensional (2D) metal carbides (MXenes) using molten inorganic salts. Surface modification of MXenes… Interests: Semiconductors Reference ID: 20-T-019 Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending