Diagnostics Research Tools Therapeutics An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV… Interests: Gene Therapy, Genomics Reference ID: 23-T-046 Desired Partnership: Co-development, Licensing IP: Patent Pending
Materials SARS-CoV-2 Therapeutics A Next-Generation mRNA Vaccine Platform For Enhancing T-Cell Responses And Improving Antiviral And Antitumor Immunity Next-generation mRNA vaccine platform uses a lipid-polymer hybrid nanoparticle to boost stability, immune cell uptake, and T cell responses, leading to stronger and longer-lasting… Interests: Biologics, Drug Delivery, Immunology, Immunotherapy, Microbiology/Virology, Oncology, Polymer, Vaccines Reference ID: 25-T-134 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Computational And Therapeutic Platform For Identifying And Correcting Unproductive Splicing To Restore Gene Expression Advanced computational tools to identify faulty RNA splicing events and design of antisense oligonucleotides to restore normal protein production in genetic diseases, especially those… Reference ID: 26-T-078 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC… Interests: Drug Development Tool, Drug Screening, Drug Target, Oncology Reference ID: 26-T-081 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics A Transcriptomic Signature Platform For Predicting Prognosis And Guiding Therapy In Ovarian Cancer Patients A 10-gene signature based on glucocorticoid receptor activity to predict survival risk in high-grade serous ovarian cancer patients, helping identify those who may benefit… Interests: Biomarker Reference ID: 26-T-022 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Glycan Proximity Sequencing (GPS) For Single-Cell Multi-omics Glycoproteomics TL;DR: Glycan Proximity Sequencing (GPS) is a next-generation single-cell multi-omics assay that measures mRNA expression, extracellular protein abundance, global glycan motifs, and protein-specific glycoforms… Interests: Biomarker Reference ID: 26-T-004 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Fatty acids In T Cell-Based Cancer Therapies Enhanced anti-tumor immunity through immunomodulation is achieved by fatty acids that activate CD8+ T cells, thereby improving cancer immunotherapy efficacy and reducing T-cell exhaustion.… Interests: Oncology, Wound Healing Reference ID: 26-T-061 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics PMO-Based RNA-Degrading Chimeras For Targeted Degradation Of α-Synuclein mRNA In Neurodegenerative Diseases Phosphorodiamidate morpholino oligomer (PMO)-based RNA-degrading chimeras reduce α-synuclein protein by degrading its messenger RNA preventing protein aggregation and propagation associated with neurodegenerative diseases. The… Interests: Biologics, Drug Development Tool, Neurology, Rare/Orphan Diseases Reference ID: 26-T-051 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Next-Generation Immunotherapy Platform With Engineered Collagen-Binding Cytokine Combinations Combination engineered IL-7 and IL-12 proteins that target tumors by binding to collagen, boosting immune attack on cancer while reducing side effects and improving… Reference ID: 23-T-119 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise… Interests: Biomarker, Drug Target, Oncology, Oncology Hematopoietic Reference ID: 25-T-162 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Antibody-Based Cell Expansion Technology For Large-Scale And Safe Amplification Of Gamma Delta T Cells Novel antibodies to rapidly and safely expand γδ T cells enabling large-scale production for cancer immunotherapies like γδ CAR-T cells, and potentially boosting these… Interests: Antibody, Antibody, Biologics, Drug Development Tool, Oncology Reference ID: 26-T-031 Desired Partnership: Co-development, Licensing IP: Patent Pending
Cleantech Materials Recoverable Non-Covalent Self-Assembling Catalysts for Hydrogen Peroxide Electrosynthesis The invention centers on a scalable, sustainable, and selective method to electrochemically generate hydrogen peroxide under mild, neutral conditions. The Unmet Need: Method for… Interests: Chemical Synthesis, Electronic Reference ID: 25-T-133 Desired Partnership: Co-development, Licensing IP: Patent Pending
