Research Tools CAM-seq: Chemical Cooperative Catalysis-Assisted M6A Sequencing More accurate, low-input mapping and quantification of RNA m⁶A modifications is achieved by CAM-seq, a chemically mild sequencing method that identifies sites at single-base… Reference ID: 24-T-220
Diagnostics Research Tools PUM-seq: Chemical Labeling Method For Single-Nucleotide Mapping of Pseudouridine Across Species Improved single-nucleotide-resolution profiling of pseudouridine across diverse RNA types is offered by a chemical-labeling and mutation-based sequencing method that detects and quantifies this modification… Interests: Sequencing Reference ID: 25-T-047
Diagnostics Research Tools DMN-seq: DEMETER-Assisted 5-Methylcytosine Nicking Sequencing Profiling From Sub-Nanogram Cell-Free DNA More sensitive methylation profiling from scarce clinical samples is supported by a sequencing method that uses 5mC-specific glycosylase activity to detect methylated sites at… Interests: Biomarker, Epigenetics, Sequencing Reference ID: 25-T-193
Research Tools Next-Generation ARTR-seq: Higher-Specificity Profiling Of RNA-Protein Interactions From Low-Input Samples A refined, antibody-guided in situ reverse-transcription sequencing method that maps RNA-binding protein binding sites with reduced background signal, building on the published ARTR-seq platform… Reference ID: 26-T-109
Research Tools RADAR: RNA Accessibility profiling via Deaminase-Annotated Reactivity Higher-sensitivity RNA accessibility and protein-binding profiling with substantially lower sequencing demand is provided by RADAR, an enzymatic probing platform that uses evolved deaminases to… Reference ID: 26-T-146
Research Tools Quantum-Enhanced Multi-Omics Platform for Personalized Medicine Advanced multi-omics platform accelerates precise and comprehensive personalized medicine by integrating high-dimensional molecular data using quantum-inspired optimization and AI/ML techniques to identify biomarkers, therapeutic… Reference ID: 26-T-064
Research Tools Therapeutics AI-Guided Genome-Wide CRISPR Platform for Novel Skin Therapeutics AI-guided CRISPR platform enables precise identification of novel therapeutic targets in primary cells, significantly enhancing drug discovery efficiency and facilitating the development of topical… Interests: Bioinformatics, Drug Development Tool, Drug Target Reference ID: 26-T-118
Diagnostics Research Tools TIGER: AI-Powered Histology-Based Gene Expression Signature Prediction for Breast Cancer TIGER is a transformer-based computational pathology pipeline that enables accurate prediction of breast cancer gene-expression signatures and neoadjuvant therapy response from routine H&E-stained histology… Reference ID: 26-T-029
Materials Research Tools Enzyme-Triggered Acylation Probes for Spatial RNA Labeling Enhanced spatial RNA labeling accuracy and efficiency through bioorthogonal acylating agents that enable precise proximity-dependent RNA modification and imaging, improving cellular RNA mapping for… Interests: Chemical Synthesis, Drug Development Tool, Tangible Property Reference ID: 24-T-225
Research Tools Therapeutics Context-Flexible Cytosine Base Editing Using An Evolved Riboflavin-Pathway Deaminase Enhanced precision in cytosine base editing by employing an evolved riboflavin biosynthesis enzyme RibD that converts targeted cytosines to thymines without intrinsic sequence-context specificity,… Interests: Gene Therapy Reference ID: 25-T-022
Research Tools Conformation-Specific HLA-F Antibodies Enable Next-Generation Immune Profiling A panel of antibody-based reagents has been developed to distinguish two conformational states of the nonclassical MHC protein HLA-F: an open conformer form and… Interests: Antibody, Biomarker, Drug Development Tool Reference ID: 22-T-062
Diagnostics Research Tools Integration Of Semiconductor-Based Components And Functionality Into Soft Microfluidics For Cell Lysis And Other Biological Applications This technology delivers precise and scalable cellular content extraction for genomic analyses by integrating semiconductor-based piezoelectric sharp tip arrays into soft microfluidics, enabling efficient… Reference ID: 21-T-034
