Diagnostics RNAmp: Ultra-Low-Input Library Construction Enabling Epitranscriptome Profiling From Scarce Samples More efficient profiling of RNA modifications, RNA–protein interactions, and translation from single-cell-scale samples is supported by an ultra-low-input RNA sequencing library method that prepares… Reference ID: 25-T-092
Diagnostics BID-seq Chemistry-Based Pseudouridine Sequencing Without Cytosine Deamination More sensitive, quantitative mapping of RNA pseudouridine at single-base resolution is provided by a mild bisulfite-based sequencing method that converts the modification into a… Reference ID: 21-T-097
Diagnostics Research Tools PUM-seq: Chemical Labeling Method For Single-Nucleotide Mapping of Pseudouridine Across Species Improved single-nucleotide-resolution profiling of pseudouridine across diverse RNA types is offered by a chemical-labeling and mutation-based sequencing method that detects and quantifies this modification… Interests: Sequencing Reference ID: 25-T-047
Diagnostics Research Tools DMN-seq: DEMETER-Assisted 5-Methylcytosine Nicking Sequencing Profiling From Sub-Nanogram Cell-Free DNA More sensitive methylation profiling from scarce clinical samples is supported by a sequencing method that uses 5mC-specific glycosylase activity to detect methylated sites at… Interests: Biomarker, Epigenetics, Sequencing Reference ID: 25-T-193
Diagnostics Therapeutics Senescent Epithelial Cell Targeting and Microbiota Therapy for IBD Improved inflammatory bowel disease (IBD) management by identifying and therapeutically targeting senescent colonic epithelial cells, thereby reducing mucosal inflammation through depletion of these pro-inflammatory… Interests: Biomarker, Drug Target, Gastrointestinal Reference ID: 26-T-174
Diagnostics Research Tools TIGER: AI-Powered Histology-Based Gene Expression Signature Prediction for Breast Cancer TIGER is a transformer-based computational pathology pipeline that enables accurate prediction of breast cancer gene-expression signatures and neoadjuvant therapy response from routine H&E-stained histology… Reference ID: 26-T-029
Diagnostics Research Tools Integration Of Semiconductor-Based Components And Functionality Into Soft Microfluidics For Cell Lysis And Other Biological Applications This technology delivers precise and scalable cellular content extraction for genomic analyses by integrating semiconductor-based piezoelectric sharp tip arrays into soft microfluidics, enabling efficient… Reference ID: 21-T-034
Diagnostics Therapeutics Tumor Aneuploidy Score As A Predictor Of Immunotherapy Response Tumor aneuploidy scoring delivers improved immunotherapy response prediction, enhancing personalized cancer treatment by providing prognostic insights beyond existing biomarkers like tumor mutational burden. The… Reference ID: 23-T-172
Diagnostics Software Slide-Level Uncertainty Quantification For Deep Learning Predictions In Digital Histopathology. The technology improves diagnostic accuracy in digital histopathology by providing slide-level uncertainty quantification for deep learning predictions, enabling more reliable and actionable clinical decision-making… Reference ID: 23-T-021
Diagnostics Software Zero-burden Risk Assessment (ZeBRA) Platform for Point-in-care Universal Screening of Complex Disorders ZeBRA is a software-based platform for universal, point-of-care risk screening that uses existing EHR data to identify patients at elevated risk for complex disorders… Reference ID: 26-T-216
Diagnostics Spectral CT Material Decomposition from Standard Single-Energy X-Ray Scans Summary This technology enables multi-material image reconstruction from conventional single-spectrum X-ray tomography data, including standard CT and tomosynthesis, without requiring dual-energy CT or photon-counting… Reference ID: 25-T-097 Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending
Diagnostics Hardware Materials Medical Devices Ultrathin, Plasmonic Schottky Biointerfaces For Wireless Stimulation And Sensing A plasmon-enhanced hierarchical gold–titania (Au-TiO₂) Schottky junction biointerface designed for wireless, energy-efficient biological stimulation (neuromodulation, cardiac pacing), real-time biosensing, and minimally invasive artificial vision.… Reference ID: 25-T-190 Desired Partnership: Co-development, Licensing IP: Patent Pending