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Overview

The Polsky Exchange incubates 15-20 companies at a time, in addition to the thousands of companies run by the Polsky Exchange’s 3,000+ members. The Polsky Exchange fosters innovation and commercialization through 34,000-square feet of shared co-working space, a state-of-the-art Fabrication Lab, and full calendar programming and workshops designed to help entrepreneurs translate their ideas into businesses.

The Space: Stats:

34,000

Square foot co-worker space

10-20

Startups housed at one time

2,500+

Members

450+

Events

Featured Events
27
Oct
Investing Essentials: Dissecting the Private Equity (PE) Industry
Monday, October 27, 2025  //  12:00 p.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
27
Oct
NVC@30 Fireside Chat: Insights from NVC Winner Matt Maloney, MBA ’10
Monday, October 27, 2025  //  12:00 p.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
27
Oct
Info Session: Venture Capital Investment Competition (VCIC)
Monday, October 27, 2025  //  5:00 p.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
27
Oct
Student Networking: Alchemist Chicago Startup Accelerator
Monday, October 27, 2025  //  5:00 p.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
28
Oct
Polsky Exchange Member Report Release Party
Tuesday, October 28, 2025  //  8:30 a.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
28
Oct
Entrepreneurship Through Acquisition (ETA) Workshop: How Searching and Operating Impacts Family Life
Tuesday, October 28, 2025  //  5:00 p.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
29
Oct
Building Your Food and Beverage Business: Allies for Community Business (A4CB) + The Hatchery Chicago
Wednesday, October 29, 2025  //  9:00 a.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time
29
Oct
Polsky Office Hours @ Booth 455 featuring Juliet Twomey
Wednesday, October 29, 2025  //  10:00 a.m.
Note: All in-person events are listed in local time; virtual events are listed in Central Time

6 UChicago Researchers to Present at Illinois Ignite

Researchers from the University of Chicago are showcasing novel technologies and innovative startups at the third biennial Illinois Ignite. The event takes place on September 22, 2022, from 9:00…

Demonstrating Commercial Promise, UChicago Researcher Recognized for Novel Cancer Drug Delivery System

University of Chicago researcher and startup founder Xiaoyang Wu has received the 2022 Duckworth Family Commercial Promise Award for his work developing a novel cancer drug delivery system. The award…

3 Startups Awarded $200,000 Each to Build Out Teams, Launch Novel Products

Flow Medical, Lismikro, and OrisDX each have been awarded a $200,000 co-investment from the George Shultz Innovation Fund to further develop their technologies. Managed by the Polsky Center for Entrepreneurship…

Compass Demo Day to Feature 5 Investor-Ready Deep Tech Startups

Polsky Science Ventures and the Compass deep tech accelerator team at the University of Chicago are hosting a “demo day” to highlight innovative research and technologies seeking growth opportunities.…

AI, Life Sciences, Quantum Tech to Get Boost as Part of the Compass Accelerator’s Latest Cohort

The Polsky Center for Entrepreneurship and Innovation is pleased to announce that six teams have been selected for the latest cohort of Compass, a deep tech accelerator program for University…

3 Novel Disease-Fighting Technologies You Should Know About Ahead of BIO 2022

Researchers at the University of Chicago have developed methods to increase the clinical efficacy of immunotherapies, provide long-lasting immune tolerance for autoimmune or transplantation therapy, and treat breast and ovarian…

Cancer Detection, Oil Spill Cleanup, Quantum Computing, and a New Medical Device: Meet the Spring 2022 Innovation Fund Finalists

Four teams have been selected as finalists for the George Shultz Innovation Fund spring 2022 investment cycle – bringing to the forefront solutions for scaling quantum computers, sustainably cleaning oil…

UChicago Spinout Super.tech Acquired by Quantum Ecosystem Leader ColdQuanta

A University of Chicago quantum software spinout and Duality Cohort 1 participant, Super.tech has been acquired by a global quantum ecosystem leader, ColdQuanta. Super.tech is embedded in Argonne National Laboratory's…

DeepTechU Day 3: Advice for Deep Tech Entrepreneurs, the Future of Immunotherapy, and Opportunities in Quantum

Day 3 of DeepTechU featured advice for entrepreneurs developing deep tech innovations, a look at the current and future immunotherapy market, and a Fireside Chat about growing the quantum…

DeepTechU Day 2: Securing VC Funding and Federal Grants that ‘Take on the Risk that the Private Market Cannot’

The second day of DeepTechU featured practical advice for deep tech startups seeking funding, including when to start conversations with venture capitalists and how to use federal government grants…

From Months to Weeks: Gene Delivery Method Improved with New ‘One-Step’ System

Delivered using adenovirus (Ad) vectors, therapeutic genes address the cause of disease – not just the symptoms. However, while advances in the understanding of human diseases and the genome have…

NIH Funds Preclinical Testing of Proposed Anti-COVID Therapy Patented By UChicago Researcher

University of Chicago researcher Raphael Lee, MD, ScD, the Paul and Allene Russell Distinguished Service Professor in the Departments of Surgery and Medicine, has patented the methods and use of…

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