Therapeutics PMO-Based RNA-Degrading Chimeras For Targeted Degradation Of α-Synuclein mRNA In Neurodegenerative Diseases Phosphorodiamidate morpholino oligomer (PMO)-based RNA-degrading chimeras reduce α-synuclein protein by degrading its messenger RNA preventing protein aggregation and propagation associated with neurodegenerative diseases. The… Interests: Biologics, Drug Development Tool, Neurology, Rare/Orphan Diseases Reference ID: 26-T-051 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Next-Generation Immunotherapy Platform With Engineered Collagen-Binding Cytokine Combinations Combination engineered IL-7 and IL-12 proteins that target tumors by binding to collagen, boosting immune attack on cancer while reducing side effects and improving… Reference ID: 23-T-119 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise… Interests: Biomarker, Drug Target, Oncology, Oncology Hematopoietic Reference ID: 25-T-162 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Antibody-Based Cell Expansion Technology For Large-Scale And Safe Amplification Of Gamma Delta T Cells Novel antibodies to rapidly and safely expand γδ T cells enabling large-scale production for cancer immunotherapies like γδ CAR-T cells, and potentially boosting these… Interests: Antibody, Antibody, Biologics, Drug Development Tool, Oncology Reference ID: 26-T-031 Desired Partnership: Co-development, Licensing IP: Patent Pending
Cleantech Materials Recoverable Non-Covalent Self-Assembling Catalysts for Hydrogen Peroxide Electrosynthesis The invention centers on a scalable, sustainable, and selective method to electrochemically generate hydrogen peroxide under mild, neutral conditions. The Unmet Need: Method for… Interests: Chemical Synthesis, Electronic Reference ID: 25-T-133 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Materials Research Tools Therapeutics New Reversible Uridine Modification Chemistry For Labeling and Functionalizing Native Nucleic Acids A chemical process that enables reversible, covalent RNA modification-highly selective for uridine enabling diverse functional group attachment, facilitating nucleic acid labeling The Unmet Need:… Interests: Bioinformatics, Biologics, Biomarker, Chemical Synthesis, Chemical Synthesis, Drug Delivery, Genomics, Imaging Agents, Medical, New Chemical Entity, Sequencing Reference ID: 25-T-126 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools Therapeutics Prolactin Receptor Antibodies For Targeted Cancer Therapy And Diagnosis Novel antibodies precisely targeting cancer cells by binding to the Prolactin Receptor (PRLR) to diagnose cancer, direct immune cells to destroy tumors, and inhibit… Interests: Antibody, Oncology Reference ID: 25-T-104 Desired Partnership: Co-development, Licensing IP: Patent Pending
Quantum Sciences Research Tools Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes Quantum nanoprobe system enables real-time probing of intracellular chemical environments and activity to advance biological and medical diagnostics The Unmet Need: Novel ways to… Interests: Drug Development Tool, Drug Screening, Sensing Reference ID: 25-T-106 Desired Partnership: Co-development, Licensing IP: Patent Pending
Medical Devices Therapeutics Hydrogel Electrochemical Platform For Controlled Localized Hydrogen Delivery A portable device that generates and stores molecular hydrogen within a hydrogel using electrodes to precisely deliver hydrogen locally to treat oxidative stress in… Interests: Dermatology Reference ID: 25-T-093 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Type I Interferons For Enhancing Chimeric Antigen Receptor T-Cell Efficacy Method to enhance CAR T-cell efficacy by incorporating low-dose exogenous IFN-α2 into CD19-directed, CD28-costimulated CAR T cells post-transduction during manufacturing boosting cytolytic molecule expression,… Interests: Immunooncology, Immunotherapy, Oncology Reference ID: 25-T-065 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Conformation-Specific Genetically Encodable Intrabodies for Spatially Modulating Protein Kinase Signaling Genetically encoded synthetic antibody fragments, expressed intracellularly, to specifically bind the mTOR FKBP12-Rapamycin binding domain inhibiting mTORC1 and mTORC2 activity. Fused with localization signals,… Interests: Antibody, Drug Development Tool Reference ID: 25-T-060 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Research Tools A High-Throughput, Label-Free Microfluidic System For Combinatorial Droplet Generation, Storage, And Analysis A microfluidic platform consisting of a two-layer PDMS system that generates and stores combinatorial droplets, enabling high-throughput screening with an integrated label-free, image-based detection… Reference ID: 25-T-014 Desired Partnership: Co-development, Licensing IP: Patent Pending
