Research Tools Therapeutics A Programmable Translational Activator Platform For Restoring Endogenous Protein Expression In Haploinsufficiency Disorders The CIRTS-4GT3 platform is a compact, programmable system that uses guide RNAs and human protein domains to boost production of specific proteins in cells,… Interests: Gene Therapy Reference ID: 24-T-204 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Therapeutics Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces… Interests: Biomarker, Oncology Reference ID: 25-T-105 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Physics-Informed Autoencoder For Non-Invasive Prediction Of Tissue Composition From MRI Data A deep learning tool that quickly and accurately estimates prostate tissue composition from MRI scans, combining physical modeling and AI to provide robust, non-invasive… Interests: Machine Learning/Artificial Intelligence Reference ID: 23-T-170 Desired Partnership: Co-development, Investment, Licensing IP: Patent Pending
Therapeutics Antibody-Polymer Conjugates For Engaging T Cells To Destroy Cancer Cells An antibody linked to a polymer that connects T cells to cancer cells enabling broad cancer targeting and effective tumor cell killing without needing… Reference ID: 25-T-108 Desired Partnership: Co-development, Licensing IP: Patent Pending
Research Tools Therapeutics Nucleic Acid Enrichment And Sequencing Method For Detecting Off-Target Base Editing Events Inrich-seq is a new method that selectively enriches and sequences inosine-containing DNA or RNA, enabling highly sensitive, genome-wide detection of off-target effects from adenine… Interests: Drug Screening, Gene Therapy Reference ID: 25-T-225 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Therapeutics A Biomarker Analysis Platform For Predicting Immunotherapy Response And Survival In Cancer Patients A method using tumor sequencing data to measure membrane-localized neoantigens, helping predict which cancer patients will benefit from immunotherapy, even those with low tumor… Interests: Biomarker, Immunotherapy, Oncology Reference ID: 22-T-017 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Mesenchymal Stem Cell And Exosome-Based Therapeutics For Restoring Ovarian Function In Premature Ovarian Insufficiency Therapeutic strategy using human mesenchymal stem cells or their exosomes to restore ovarian function and fertility in premature ovarian insufficiency by promoting cell growth,… Reference ID: 21-T-075 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics Nanoparticles Containing Multiple Cleavable Prodrugs For Cancer Therapy Specially designed nanoparticles to deliver multiple cancer drugs at once, improving drug stability, targeting tumors more effectively, and reducing side effects by controlling and… Interests: Chemical Synthesis, Combination Therapy, Drug Delivery Reference ID: 21-T-018 Desired Partnership: Co-development, Licensing IP: Patent Pending
Diagnostics Medical Devices Automated Microfluidic Platform For High-Throughput 3D Cell Culture, Dynamic Stimulation, And Single-Cell Analysis Automated microfluidic platform enabling high-throughput, precise 3D cell and organoid culture, drug screening, and single-cell analysis, allowing real-time monitoring and dynamic control of cellular… Interests: Cell Line Reference ID: 18-T-053 Desired Partnership: Co-development, Licensing IP: Patent Issued
Therapeutics Small Molecule Therapeutics For Inhibiting Carotid Body Hypersensitivity To Treat Sleep-Related Breathing Disorders New compounds that inhibit an enzyme to reduce hydrogen sulfide in the carotid body, helping to normalize breathing and prevent sleep apnea by targeting… Interests: Small Molecules Reference ID: 16-T-123 Desired Partnership: Co-development, Licensing IP: Patent Issued
Therapeutics Lymphangiogenesis For Therapeutic Immunomodulation A vaccine platform that uses engineered lymphangiogenesis factors and antigens to stimulate lymphatic endothelial cells, creating strong, long-lasting immune memory or tolerance with fewer… Interests: Biologics, Immunotherapy, Oncology Reference ID: 16-T-059 Desired Partnership: Co-development, Licensing IP: Patent Pending
Therapeutics A Gene-Modified T Cell Platform For Spatially Controlled Therapeutic Protein Delivery In Response To Radiation Engineered T cells to release cancer-killing proteins only when activated by targeted radiation, enabling precise, localized tumor treatment while minimizing side effects and improving… Interests: Immunooncology, Oncology, Oncology Radiotherapy Reference ID: 24-T-191 Desired Partnership: Co-development, Licensing IP: Patent Pending