Software Longitudinal Geo-Coded U.S. Phonebook Data Platform This technology delivers precise historical insights and enhanced data accessibility through a digitized, geocoded, and longitudinally linked dataset of U.S. businesses and households from… Reference ID: 27-T-033
Education Software iCAT: AI-Driven GIS Platform for Analyzing Health Disparities The Intelligent Catchment Analysis Tool (iCAT) enhances health outcomes and resource allocation in underserved communities by employing artificial intelligence and geographic information system analytics… Reference ID: 25-T-084
Medical Devices Software AI-Driven Medical Imaging System for Health Disparity Detection Medical imaging artificial intelligence probe offering enhanced detection, continuous monitoring, and quantitative analysis of health disparities across populations by leveraging large datasets and advanced… Reference ID: 24-T-199
Diagnostics Research Tools TIGER: AI-Powered Histology-Based Gene Expression Signature Prediction for Breast Cancer TIGER is a transformer-based computational pathology pipeline that enables accurate prediction of breast cancer gene-expression signatures and neoadjuvant therapy response from routine H&E-stained histology… Reference ID: 26-T-029
Diagnostics Therapeutics Senescent Epithelial Cell Targeting and Microbiota Therapy for IBD Improved inflammatory bowel disease (IBD) management by identifying and therapeutically targeting senescent colonic epithelial cells, thereby reducing mucosal inflammation through depletion of these pro-inflammatory… Interests: Biomarker, Drug Target, Gastrointestinal Reference ID: 26-T-174
Research Tools Therapeutics AI-Guided Genome-Wide CRISPR Platform for Novel Skin Therapeutics AI-guided CRISPR platform enables precise identification of novel therapeutic targets in primary cells, significantly enhancing drug discovery efficiency and facilitating the development of topical… Interests: Bioinformatics, Drug Development Tool, Drug Target Reference ID: 26-T-118
Research Tools Quantum-Enhanced Multi-Omics Platform for Personalized Medicine Advanced multi-omics platform accelerates precise and comprehensive personalized medicine by integrating high-dimensional molecular data using quantum-inspired optimization and AI/ML techniques to identify biomarkers, therapeutic… Reference ID: 26-T-064
Therapeutics Microbiome-Based Stratification and Lactulose Therapy for Infection Prevention in Advanced Liver Disease Improved survival and reduced systemic infections in advanced liver disease patients by expanding gut Bifidobacteria through lactulose administration, leveraging metabolomic profiling to stratify candidates… Interests: Microbiome Reference ID: 23-T-112
Materials Research Tools Enzyme-Triggered Acylation Probes for Spatial RNA Labeling Enhanced spatial RNA labeling accuracy and efficiency through bioorthogonal acylating agents that enable precise proximity-dependent RNA modification and imaging, improving cellular RNA mapping for… Interests: Chemical Synthesis, Drug Development Tool, Tangible Property Reference ID: 24-T-225
Therapeutics Nanoparticle Delivery of Stabilized Synthetic Transcriptional Repressors for Targeted Gene Regulation Enhanced control of disease-associated gene expression through nanoparticle delivery of stabilized DNA-binding peptides and miniproteins, improving targeted transcriptional regulation The Unmet Need: Efficient and specific… Interests: Drug Delivery Reference ID: 23-T-156
Therapeutics Covalent Pan-Kinase Inhibitors and Live-Cell Activity Probes A cell-permeable, covalent multikinase activity probe that enhances selective kinase detection in native cellular environments, enabling precise profiling of kinase targets and inhibitor engagement… Interests: Cardiovascular, Dermatology, Inflammatory, Neurology, New Chemical Entity, Oncology Reference ID: 25-T-024
Research Tools Therapeutics Evolved riboflavin biosynthesis enzyme RibD as a novel nucleic acid deaminase for base editing. Enhanced precision in cytosine base editing by employing an evolved riboflavin biosynthesis enzyme RibD that converts targeted cytosines to thymines without intrinsic sequence-context specificity,… Interests: Gene Therapy Reference ID: 25-T-022
