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Polsky Center for Entrepreneurship and Innovation
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Up to $130 Million to Fuel Drug Discovery and Development at the UChicago
Polsky Center for Entrepreneurship and Innovation
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Edward L. Kaplan, ’71, New Venture Challenge Winner Simple Mills Acquired by Flower Foods for $795 Million
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Polsky Center for Entrepreneurship and Innovation
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Polsky Center Receives Outstanding Contributions to Venture Creation Award
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Venture Success
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The Hiring Process is Now an AI Arms Race, but There's Still Room to Restore the Human Element
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How Theta Neurotech is Making Seizure Prediction Possible
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How to Become a Successful CEO
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Science and Technology Commercialization
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Midwest Biotech Startup Showcase Spotlights 30+ Breakthrough Innovations from Leading Research Institutions
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Fall 2025 Collaboratorium Connects Researchers and Business Expertise
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Novel Medical Device Provides Custom, Cost-Effective Solution for Atrial Fibrillation Patients
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Community Impact
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Small Business Spotlight: Tati’s Floral is Bringing Beauty to Chicago’s South Side
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Remembering Ed Kaplan: A Legacy of Innovation, Generosity, and Lasting Impact
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Small Business Spotlight: How Diversity Connected Helps Companies Turn Chaos into Clarity
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Announcements
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Polsky Center Welcomes 2026 Cohort of the Small Business Growth Program
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Polsky Center Welcomes Newest Cohort of the Small Business Financial Fundamentals Program
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Midwest Biotech Startup Showcase Spotlights 30+ Breakthrough Innovations from Leading Research Institutions
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Events
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Midwest Biotech Startup Showcase Brings Next Wave of Innovation to San Francisco
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Midwest Biotech Startup Showcase Spotlights 30+ Breakthrough Innovations from Leading Research Institutions
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NVC@30 Fireside Chat with David Rabie Spotlights Tovala’s Journey from NVC to a Profitable, 9-Figure Revenue Business
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##POLSKY ON DEMAND

Polsky On Demand – an online portal that provides access to some of Polsky’s world-class business and entrepreneurship educational workshops for free. Browse our digital library below for educational content around entrepreneurship essentials, small business workshops, entrepreneurship through acquisition (ETA), and much more!

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#VIEW POLSKY PODCAST

ETA Insider Podcast series features all things related to entrepreneurship through acquisition. Where Are They Now? delves into the entrepreneurial journeys of several startups to mark the 25th anniversary of the Edward L. Kaplan, ’71, New Venture Challenge, a top-ranked startup accelerator at the University of Chicago.

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Midwest Biotech Startup Showcase Brings Next Wave of Innovation to San Francisco

More than 35 high-growth biotech startups from across the Midwest gathered in San Francisco this week for the Midwest Biotech Startup Showcase, co-hosted by the Polsky Center for Entrepreneurship and…

Polsky Center Welcomes 2026 Cohort of the Small Business Growth Program

The Polsky Center for Entrepreneurship and Innovation is welcoming the newest cohort of businesses to the Polsky Exchange Small Business Growth Program, a nine-month initiative designed to help established…

The Hiring Process is Now an AI Arms Race, but There’s Still Room to Restore the Human Element

The following article was written by Scott Holloway, general partner at Starting Line and entrepreneur-in-residence at the Polsky Center, and originally published in Crain's Chicago Business on December 22,…

Polsky Center Welcomes Newest Cohort of the Small Business Financial Fundamentals Program

The Polsky Center for Entrepreneurship and Innovation is welcoming a new cohort of entrepreneurs to the Polsky Exchange Small Business Financial Fundamentals program. The 10-week program is designed to…

Midwest Biotech Startup Showcase Spotlights 30+ Breakthrough Innovations from Leading Research Institutions

Bringing breakthrough science to the forefront of innovation, the Midwest Biotech Startup Showcase will highlight more than 30 emerging life sciences and biotech ventures from leading research institutions across…

How Local Stores Can Thrive this Holiday Season

The following article was written by Abigail Ingram, executive director of the Polsky Exchange, and originally published in Crain's Chicago Business on November 17, 2025. Read the original article.…

NVC@30 Fireside Chat with David Rabie Spotlights Tovala’s Journey from NVC to a Profitable, 9-Figure Revenue Business

The Polsky Center continued its NVC@30 Fireside Chat series with David Rabie, MBA ’15, founder and CEO of Tovala and winner of the 2015 Edward L. Kaplan, ’71 New Venture…

ETA’s Global Momentum Takes Center Stage at Record-Breaking 12th Annual Booth–Kellogg Conference

This week the Polsky Center, the ETA Group at Chicago Booth, and the Kellogg Innovation and Entrepreneurship Initiative hosted the 12th Annual Entrepreneurship Through Acquisition Conference, welcoming more than 1,100…

Polsky Center Announces Teams Selected for the 14th Annual College New Venture Challenge

The Polsky Center for Entrepreneurship and Innovation is pleased to announce the teams selected for the 14th annual College New Venture Challenge (CNVC), an undergraduate student startup accelerator. This year’s…

Balancing Pre- and Post-Letter of Intent Diligence in ETA: Strategy, Tradeoffs, and Winning the Auction

Sponsored Content // Balancing diligence before and after signing a letter of intent (LOI) is one of the most important — and often overlooked — aspects of entrepreneurship through acquisition…

How Theta Neurotech is Making Seizure Prediction Possible

Every year, thousands of epilepsy patients lose their lives unexpectedly — often with no warning that a seizure is even coming. It’s a terrifying reality for the more than 3…

Fireside Chat with Perplexity AI’s Aravind Srinivas Offers Look into the Future of AI

Last week the Polsky Center for Entrepreneurship and Innovation welcomed Aravind Srinivas, CEO and cofounder of Perplexity AI, for a fireside chat on the future of artificial intelligence, the acceleration…
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