Tolerizing Agonist/Immunomodulator Loaded Liposomes for Long-Lived Immune Tolerance
SUMMARY A failure of central immune tolerance typically driven by autoantigen specific T regulatory (Treg) cells is the primary cause of many autoimmune diseases. This technology generates antigen specific immune tolerance for autoimmune or transplantation therapy via induction of tolerogenic dendritic cells (tolDC, PD-L1+, CD80- CD11c+)) which facilitate the… Read More