Page Venture Gallery Venture Gallery View startups founded from across the University of Chicago ecosystem in a range of industries. Welcome to the Venture Gallery! The Polsky Center provides “first look” and early...
Technology Nucleic Acid Enrichment And Sequencing Method For Detecting Off-Target Base Editing Events Inrich-seq is a new method that selectively enriches and sequences inosine-containing DNA or RNA, enabling highly sensitive, genome-wide detection of off-target effects from adenine base editing in human cells The…
Technology Context-Specific Cytosine Base Editors For Precise Single-Nucleotide DNA Editing Engineered TadA deaminase via directed evolution to produce CRISPR cytosine base editors that precisely convert target cytosines to thymines in specific DNA contexts with high efficiency and minimal off-target effects…
News ExplORer Surgical, Chicago-based Health Tech Startup, Raises $1 Million Explorer Surgical, which aims to be an interactive playbook for surgeons and staff, has raised a $1 million to bring it a step closer to use in operating rooms. Read...
Technology Evolved riboflavin biosynthesis enzyme RibD as a novel nucleic acid deaminase for base editing. Enhanced precision in cytosine base editing by employing an evolved riboflavin biosynthesis enzyme RibD that converts targeted cytosines to thymines without intrinsic sequence-context specificity, thereby expanding genomic editing flexibility and…
Technology Nanomaterial Based Intracellular Drug Delivery Of Therapeutic Peptides Intracellular delivery involves introduction of small biomolecules, nucleic acids, proteins, synthetic nanomaterials and drugs into the cell. There is a lot of focus on targeted intracellular delivery for improved therapy…
Technology Fatty acids In T Cell-Based Cancer Therapies Enhanced anti-tumor immunity through immunomodulation is achieved by fatty acids that activate CD8+ T cells, thereby improving cancer immunotherapy efficacy and reducing T-cell exhaustion. The Unmet Need: Limited effectiveness of current…
News Life Sciences Community Convenes at Chicago BioCapital Summit in a Showcase of Local Innovation Hosted by the Chicago Biomedical Consortium (CBC), the inaugural Chicago BioCapital Summit this week brought together industry, academia, and investors in a showcase of the latest innovations in the life...
Technology Universal TaqMan-Based Detection System for RNA Quantification Reverse transcriptase quantitative PCR (qPCR) effectively quantifies coding and noncoding RNA expressions in cells and tissue samples. Among various RT-qPCR detection systems, SYBR Green-based system is most commonly used, although…
Page Polsky Council The Polsky Council comprises many of the country’s leading entrepreneurs, venture capitalists, and private equity investors, who provide ongoing guidance and support to the Polsky Center.
Program Collaboratorium Showcase your research, technology, or ideas and develop a better understanding of the next steps to pursue a business opportunity.
