Patent of the Week: Improving Post-CPR Outcomes in Heart Attack Patients

Patent of the Week

Cardiogenic shock occurs when the heart has been damaged and is unable to pump enough blood. It is a common cause of death, usually brought on by a severe heart attack. It also can occur after a patient receives CPR, though why this happens is not well understood and current treatments that restore heart function do not protect against long term damage.

An associate professor of medicine at the University of Chicago, Willard Sharp combines his clinical practice with an NIH-funded translational research program focused on developing novel therapies.

Through this research he has demonstrated that the main mechanism leading to post-CPR cardiogenic shock is myocardial stunning, which is specifically caused by mitochondrial damage.

To help improve post-CPR outcomes in cardiac arrest patients, Sharp has invented a novel treatment method that involves the administration of novel small molecules that inhibits myocardial stunning.

The patent-pending method addresses a novel mechanism of action for cardiogenic shock, reduces neurological damage, and improves a patient’s overall long-term outcome following CPR.

// Read more:

// Patent of the Week is a weekly column highlighting research and inventions from University of Chicago faculty.

This site uses cookies and other tracking technologies to assist with navigation and your ability to provide feedback, analyze your use of products and services, assist with our promotional and marketing efforts.