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Polsky Center for Entrepreneurship and Innovation
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Up to $130 Million to Fuel Drug Discovery and Development at the UChicago
Polsky Center for Entrepreneurship and Innovation
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Edward L. Kaplan, ’71, New Venture Challenge Winner Simple Mills Acquired by Flower Foods for $795 Million
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Polsky Center for Entrepreneurship and Innovation
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Polsky Center Receives Outstanding Contributions to Venture Creation Award
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Venture Success
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How to Become a Successful CEO
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How Rayni Turned Scientific Frustration Into a Victory at the 2025 New Venture Challenge
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Zenblen’s Smooth Rise from Office Blender to Robotic Smoothie Bar
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Science and Technology Commercialization
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Fall 2025 Collaboratorium Connects Researchers and Business Expertise
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Novel Medical Device Provides Custom, Cost-Effective Solution for Atrial Fibrillation Patients
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The Missing Piece: Epinoma Advances Novel Disease Detection Tech
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Community Impact
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Small Business Spotlight: Tati’s Floral is Bringing Beauty to Chicago’s South Side
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Remembering Ed Kaplan: A Legacy of Innovation, Generosity, and Lasting Impact
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Small Business Spotlight: How Diversity Connected Helps Companies Turn Chaos into Clarity
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Announcements
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The Polsky Exchange Year in Review 2024
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The Polsky Center Welcomes the 2025 Innovate2Market Cohort
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Polsky Science and Technology Associates Helping Drive University Innovation Forward
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Events
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NVC@30 Fireside Chat with Grubhub Cofounder Matt Maloney Highlights the Power of Persistence
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10 Small Businesses Graduate from Polsky Center’s Small Business Growth Program
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Polsky Exchange and Huntington Bank Help Secure Funding for South Side Entrepreneurs
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##POLSKY ON DEMAND

Polsky On Demand – an online portal that provides access to some of Polsky’s world-class business and entrepreneurship educational workshops for free. Browse our digital library below for educational content around entrepreneurship essentials, small business workshops, entrepreneurship through acquisition (ETA), and much more!

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#VIEW POLSKY PODCAST

ETA Insider Podcast series features all things related to entrepreneurship through acquisition. Where Are They Now? delves into the entrepreneurial journeys of several startups to mark the 25th anniversary of the Edward L. Kaplan, ’71, New Venture Challenge, a top-ranked startup accelerator at the University of Chicago.

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NVC@30 Fireside Chat with Grubhub Cofounder Matt Maloney Highlights the Power of Persistence

The Polsky Center kicked off its NVC@30 Fireside Chat series with one of the more prominent faces of the New Venture Challenge — Matt Maloney, MBA ’10, cofounder of Grubhub…

The Polsky Exchange Year in Review 2024

2024 Polsky Exchange Summary Report In 2024 the Polsky Exchange continued to be a cornerstone of innovation and entrepreneurship on Chicago’s South Side. Through its work and meeting spaces,…

How First-Time ETA Buyers Can Navigate Today’s Complex SBA Lending Market

Sponsored Content // Buying your first business is one of the most exciting parts of entrepreneurship-through-acquisition (ETA), but navigating the process can also be one of the most complex. In…

The Polsky Center Welcomes the 2025 Innovate2Market Cohort

The Polsky Center is welcoming the latest cohort of Innovate2Market, a five-week program designed to help community inventors and innovators explore the commercial potential and impact of their products…

Polsky Science and Technology Associates Helping Drive University Innovation Forward

The new cohort of the Polsky Science and Technology Associates includes three University of Chicago graduate students who are working with the Polsky Center’s technology and business development teams…

Meet the Inaugural Alchemist Chicago Cohort

Alchemist Accelerator and the University of Chicago’s Polsky Center for Entrepreneurship and Innovation are thrilled to announce the inaugural cohort of Alchemist Chicago. Alchemist Chicago Cohort 1 is made…

Impact in Action: Polsky Center Year in Review (FY25)

2024-2025 Polsky Center Impact Report This past year (July 1, 2024 to June 30, 2025) at the Polsky Center was defined by momentum — from advancing innovation and entrepreneurship…

How to Become a Successful CEO

The following article was written by Steven Kaplan, the Neubauer Family Distinguished Service Professor of Entrepreneurship & Finance at Chicago Booth School of Business and Kessenich E.P. Faculty Director…

Bluefors Opens Shared Lab Facility at the UChicago Science Incubator, Expands Bluefors Lab Chicago

Bluefors, the world leader in cryogenic cooling systems for quantum technology, has opened a second Chicago-based lab facility at the UChicago Science Incubator located at Hyde Park Labs. The…

Fall 2025 Collaboratorium Connects Researchers and Business Expertise

  Connecting researchers and scientists with business expertise, the Fall 2025 Collaboratorium will feature teams participating in the Polsky I-Corps program in addition to startups from other areas of the…

Novel Medical Device Provides Custom, Cost-Effective Solution for Atrial Fibrillation Patients

Founded by an interventional cardiologist at the University of Chicago, Parasol has developed a novel, minimally invasive device to reduce the risk of stroke in patients with atrial fibrillation. At…

Hyde Park Labs, UChicago Science Incubator Add to Growing Ecosystem for Founders on the South Side

The University of Chicago this week celebrated the opening of Hyde Park Labs and its new UChicago Science Incubator — advancing the University’s long-term vision to bring world-class research, entrepreneurial…
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