Microbiology/Virology

A Next-Generation mRNA Vaccine Platform For Enhancing T-Cell Responses And Improving Antiviral And Antitumor Immunity

SUMMARY Next-generation mRNA vaccine platform uses a lipid-polymer hybrid nanoparticle to boost stability, immune cell uptake, and T cell responses, leading to stronger and longer-lasting protection against viruses and cancer while maintaining strong antibody responses The Unmet Need: Intracellular delivery of mRNA… Read More

A Novel Class of Antibodies For The Development Of Universal Influenza Vaccines

SUMMARY Influenza viruses remain a global health problem, with antigenically drifting seasonal viruses and the constant risk of zoonotic influenza virus spillovers into humans. Antibodies against the major surface glycoprotein hemagglutinin (HA) are critical for providing protection against influenza virus infection. HA is divided into two domains: the globular head… Read More