A Prognostic Gene Signature for Predicting Chemotherapy Sensitivity and Patient Survival in ER-negative Breast Cancer
SUMMARY ER-negative (ER-) breast cancers make up 20% of all breast cancer diagnosis. However, no gene signature exists for predicting drug sensitivity and prognosis. Therefore, the clinical standard remains treating patients with generic chemotherapy despite possible drug resistance. Glucocorticoid receptor (GR) regulates many genes that contribute to tumor viability, aggressiveness,… Read More