Technology Targeting TGFβ Signaling for Enhancing Cancer Radiotherapy and Immunotherapy Efficacy The method leverages a negative regulator to inhibit TGFβ signaling in myeloid cells, potentially enhancing the efficacy of radiotherapy and immunotherapy in cancer treatment by reducing immune suppression. The problem:…
Technology Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling pathways relevant to cancer diagnosis and…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
Technology Permeable junction-enhanced roll-to-roll microfabrication for electronic devices A scalable roll-to-roll microfabrication method using salt-assisted photochemical patterning and permeable junctions for rapid, eco-friendly production and transfer of carbon-based devices onto flexible substrates. Enables cost-efficient, high-performance bioelectronics and catalytic…
Technology Next-gen Immunoregulatory Bioelectronic Patch For Skin Inflammation An electronic system that incorporates living materials as an interfacial layer, specially tailored for managing skin inflammation diseases. The Unmet Need: Chronic skin diseases lack safe, drug-free, continuous monitoring and…
Technology A Precision Nanomedicine Platform For Pulmonary And Organ Fibrosis A targeted nanomedicine platform for delivering therapeutics to activated fibroblasts in pulmonary fibrosis and other fibrotic diseases The Unmet Need: Current pulmonary fibrosis therapies slow decline for some patients but…