Technology RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise and effective leukemia treatments The Unmet…
Program Past Participants 2025 Folasade Rancie – Doulala Michael Gustafson – Three Pillars Sudanshu Kaushik – Exalt Data Randel Bennett – Qixent Laurel Alpaugh – Coclo Ritu Sreenivasan – Mooj Foods Shikhar Pandey…
News Solarmer Energy Inc. Expects Sun to Shine on Chicago Invention Solarmer Energy Inc. is developing plastic solar cells for portable electronic devices that will incorporate technology invented at the University of Chicago. The company is on track to complete a...
News Innovation Fund Invests $575,000 in Biotech Companies The University of Chicago Innovation Fund announced plans to invest up to $575,000 into three biotechnology companies—ImmunArtes, Onchilles Pharma, and Oxalo Therapeutics. These latest investments bring the Innovation Fund’s total...
News 2019-2020 Polsky Founders’ Fund Fellowship Cohort Announced The program provide entrepreneurs with funding to sustain momentum on ventures.
News 6 UChicago Researchers to Present at Illinois Ignite Researchers from the University of Chicago are showcasing novel technologies and innovative startups at the third biennial Illinois Ignite. The event takes place on September 22, 2022, from 9:00 a.m....
Technology A Non-Hormonal Therapeutic Platform For Targeting M6A Regulators To Treat Uterine Fibroids A non-hormonal therapeutic strategy for uterine fibroids targeting the upregulated m6A regulator METTL3 employing small molecule inhibitors thereby reducing fibroid cell proliferation and increasing apoptosis. The Unmet Need: Novel…
Technology A New Genetic Medicine Strategy For Treating Neurological Disorders Synaptic transmission and plasticity are fundamental to neuronal functions, and alterations of synaptic protein expression are direct causes of autism, intellectual disability (ID), and epilepsy. De novo loss-of-function (LoF) mutations…
Technology A Computational And Therapeutic Platform For Identifying And Correcting Unproductive Splicing To Restore Gene Expression Advanced computational tools to identify faulty RNA splicing events and design of antisense oligonucleotides to restore normal protein production in genetic diseases, especially those affecting the brain The Unmet Need:…
Technology An Innovative Cutaneous Gene Therapy Platform For Metabolic Disorders The field of metabolic disease treatment has long been challenged by the need for precise, long-term regulation of critical hormones and proteins that manage glucose homeostasis and energy balance. Current…
Technology Process for the Low Cost and Non-Toxic Isolation of Cellulose Nanofibers from Grass Biomass Cellulose nanofibers are a class of nanocellulose that are favored in materials applications because of their desirable chemical, mechanical, and environmental properties. However, the isolation of these materials from biomass…
Technology Novel Material for Skin Wound Closure and Scar Prevention Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States, there are 1.1 million burn injuries…
