News Psyonic Racks Up Accolades as its Bionic Hand Prepares for Nationwide Launch An Illinois startup that has developed a more affordable bionic hand has been racking up accolades as it prepares for the nationwide rollout of its high-tech prosthetic. Psyonic, which this...
Technology Context-Specific Cytosine Base Editors For Precise Single-Nucleotide DNA Editing Engineered TadA deaminase via directed evolution to produce CRISPR cytosine base editors that precisely convert target cytosines to thymines in specific DNA contexts with high efficiency and minimal off-target effects…
News Clarix Imaging Addresses Unmet Needs with Novel Imaging-Based Solution for Surgical Oncology Clarix Imaging was founded in 2016 as a spin-off company from the University of Chicago – translating decades of research in advanced medical imaging theory and techniques out of professor...
News Clarix Imaging Gets $10 Million to Scale FDA-Cleared 3D Imaging Tech University of Chicago spinout Clarix Imaging has received $10 million in funding from kineo finance, a Swiss-headquartered investment firm, to advance its novel imaging-based solution for surgical oncology. The company, which...
Team Han Sun, PhD Assistant Director, Business Development, The Duckworth Family Cancer Fellow Assistant Director, Business Development, The Duckworth Family Cancer Fellow
Technology PMO-Based RNA-Degrading Chimeras For Targeted Degradation Of α-Synuclein mRNA In Neurodegenerative Diseases Phosphorodiamidate morpholino oligomer (PMO)-based RNA-degrading chimeras reduce α-synuclein protein by degrading its messenger RNA preventing protein aggregation and propagation associated with neurodegenerative diseases. The Unmet Need: More potent and selective…
Technology A New Genetic Medicine Strategy For Treating Neurological Disorders Synaptic transmission and plasticity are fundamental to neuronal functions, and alterations of synaptic protein expression are direct causes of autism, intellectual disability (ID), and epilepsy. De novo loss-of-function (LoF) mutations…
Technology Gene Splice-Switching Technology for Treating CACNA1A-Associated Neurological Diseases This technology regulates the expression of the CACNA1A gene, which encodes a neuronal calcium channel subunit, by redirecting alternative splicing to treat related neurological diseases. This approach can potentially correct…
Technology A Computational And Therapeutic Platform For Identifying And Correcting Unproductive Splicing To Restore Gene Expression Advanced computational tools to identify faulty RNA splicing events and design of antisense oligonucleotides to restore normal protein production in genetic diseases, especially those affecting the brain The Unmet Need:…
Technology An Innovative Cutaneous Gene Therapy Platform For Metabolic Disorders Versatile cutaneous gene therapy platform through skin transplants to stably deliver GLP-1 and other protein factors to treat metabolic disorders The Unmet Need: Long-lasting, safe, and effective gene therapy…
Technology Novel Material for Skin Wound Closure and Scar Prevention Burn injuries are among the most devastating of all injuries and are the fourth most common type of trauma worldwide. In the United States, there are 1.1 million burn injuries…
