Technology A Novel Class of Antibodies For The Development Of Universal Influenza Vaccines Influenza viruses remain a global health problem, with antigenically drifting seasonal viruses and the constant risk of zoonotic influenza virus spillovers into humans. Antibodies against the major surface glycoprotein hemagglutinin…
Technology A Highly-Efficient Platform To Form Vesicular Polymer Nanoparticles For RNA And Protein Payload Delivery Polymersomes are a type of nanoscale vesicle made from block copolymers and can encapsulate a variety of therapeutic agents including proteins and nucleic acids. These nanovesicles are assembled at room…
Technology Diagnostic Assays And Engineered Compositions For Detecting Angiotensin II Autoantibodies And Preventing Coronavirus Autoimmunity Detection and monitoring of autoantibodies against Angiotensin II in COVID-19 patients, guiding diagnosis, treatment, and vaccine design to reduce blood pressure complications and prevent harmful autoimmune responses linked to the…
News 30 Teams Advance to Phase II of the 2024 Edward L. Kaplan, ’71, New Venture Challenge Today, the Polsky Center for Entrepreneurship and Innovation announced the 30 Phase II teams advancing in the 2024 Edward L. Kaplan, ’71, New Venture Challenge (NVC), the University of Chicago’s...
Technology Fully Synthetic Adjuvant Delivery System For Enhanced Tumor-Targeted Immunotherapy A cancer vaccine that enhances immune response by directly binding adjuvants to tumor cells, avoiding targeting antibodies, and reducing related side effects The problem: Therapeutic vaccination has long been a…
News Life Sciences Community Convenes at Chicago BioCapital Summit in a Showcase of Local Innovation Hosted by the Chicago Biomedical Consortium (CBC), the inaugural Chicago BioCapital Summit this week brought together industry, academia, and investors in a showcase of the latest innovations in the life...
Technology Prophylactic Strategy For C. Difficile Infection Prevention This technology is a prevention method for those at risk of C. difficile infection using a mutated strain of C. difficile that reduces toxicity and competes with virulent strains, offering…
Technology RNA Editing Technology for Enhancing Tumor Immunogenicity and Immune Checkpoint Inhibitors Novel RNA editing method to generate a multitude of neoantigens in tumor cells making the cells more recognizable by T cells and enhancing the efficacy of immune checkpoint inhibitors The…
Technology Broadly Neutralizing Neuraminidase Antibodies for Prophylactic and Therapeutic Treatment of Influenza One of the weaknesses of current influenza vaccines is seasonable variability in efficacy, which is predominantly caused by escape mutations in the hemagglutinin (HA) antigen, the main target of the…
News Reluctant Renaissance Man Even though Olaf Schneewind operates seamlessly in many overlapping scientific, academic and corporate circles, he denies being a Renaissance Man. “I’m just a complete workaholic, 365 days of the year,”...
News Polsky Supports 13 STEM Projects in Spring 2020 I-Corps Program Cohort The Polsky Center for Entrepreneurship and Innovation is pleased to announce the latest cohort of its Polsky I-Corps program, a 7-week highly-experiential program designed to empower UChicago scientists, researchers, and...
News Record $1.6 Million Awarded in the 25th Anniversary Finals of Chicago Booth’s New Venture Challenge; First-Place Winner Andes STR Lands More Than $660,000 The Polsky Center for Entrepreneurship and Innovation at the University if Chicago has announced a record-breaking investment of $1.6 million in the winners of the 2021 Edward L. Kaplan, ’71, New...