News UChicago Science Incubator to Provide ‘On-Ramp’ Facilities to Accelerate Tenant Entry into IQMP Quantum Ecosystem The Illinois Quantum and Microelectronics Park (IQMP), a first-of-its-kind park built for quantum technology scale-up and advanced microelectronics research and development, has announced that the University of Chicago Science Incubator...
Event Align Your Team, Accelerate Your Growth: A Workshop for Entrepreneurs March 31, 2026 Entrepreneurs and small business teams don’t have time—or money—to waste. These four questions show up again and again in small businesses: ● “How do we make progress when the work...
News CavilinQ Secures $8.8M Seed Round to Unlock Utility-Scale Quantum Computing CavilinQ has raised $8.8 million in seed funding to develop scalable quantum computing architecture based on pioneering research at the University of Chicago. The round was led by QVT, with...
Program AI Research Commons Midwest Fellows Program Accelerate AI startups through technical resources, mentorship, investor connections, and commercialization support.
News NVC@30 Fireside Chat with Sebastian Rivas Explores Building Andes from NVC Winner to Real Estate Asset Platform As part of the NVC@30 Fireside Chat series, the Polsky Center welcomed Sebastian Rivas, MBA ’21, founder and CEO of Andes, to discuss his entrepreneurial journey, his experience in the...
Technology A Programmable Translational Activator Platform For Restoring Endogenous Protein Expression In Haploinsufficiency Disorders The CIRTS-4GT3 platform is a compact, programmable system that uses guide RNAs and human protein domains to boost production of specific proteins in cells, offering a safe and targeted therapy…
Technology Novel Aqueous Chemical Stabilization Method for Proteins Based on the Diels-alder Reaction Stabilization of therapeutic proteins and peptides is often necessary to improve pharmacokinetic properties and reduce proteolysis in vivo. However, pre-existing stabilization strategies require expensive catalysts or harsh reagents that prevent…
Technology A Low Dose, Multi-drug Cocktail for the Treatment of Metastatic and Resistant Breast Cancers An estimated 20-30% of breast cancer patients suffer from metastatic recurrence, which can be perpetuated by an overreliance on high doses of a single drug during initial treatment. In addition…
Technology An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV delivery. The unmet Need: New CRISPR-systems…
Technology Bioorthogonal Enzyme-Probe System For Spatially Specific Biomolecule Labeling Novel proximity labeling technology utilizes a bioorthogonal protecting group, impervious to endogenous esterases, paired with evolved BS2 esterase mutants. The enzyme-mediated unmasking creates a reactive acid chloride intermediate that rapidly…
Technology Novel Platform for Allosterically Modifying Enzyme Specificty Fine tuning enzyme specificity is desired for industrial catalysis. Enzymes lacking structural characterization or favorable recombinant expression are not amenable to traditional directed evolution or de novo design approaches. “Monobodies”…
Technology Functionalized Metal Carbides For Energy Storage The invention is a novel synthetic approach for surface modification of two-dimensional (2D) metal carbides (MXenes) using molten inorganic salts. Surface modification of MXenes have been hypothesized to affect material…
