Technology Nanoparticles Containing Multiple Cleavable Prodrugs For Cancer Therapy Specially designed nanoparticles to deliver multiple cancer drugs at once, improving drug stability, targeting tumors more effectively, and reducing side effects by controlling and triggering drug release directly at the…
Page Venture Gallery Venture Gallery View startups founded from across the University of Chicago ecosystem in a range of industries. Welcome to the Venture Gallery! The Polsky Center provides “first look” and early...
News NanoPattern Receives $1 Million NSF Grant: ‘A Validation of Our Vision,’ Says Cofounder NanoPattern Technologies recently received a $999,428 grant from the National Science Foundation’s (NSF) Phase II Small Business Innovation Research (SBIR) grant program. Cofounded by Dmitri Talapin, Ernest DeWitt Burton Distinguished Service...
Technology Injectable Calcium Phosphate Amorphous Nanoparticle Pastes for Orthopedic Applications Calcium phosphates have chemical similarity to bones and teeth, and as such, these compounds are highly desired for orthopedic and dental implant applications. However, current formulations have limited bioavailability and…
Technology A Highly-Efficient Platform To Form Vesicular Polymer Nanoparticles For RNA And Protein Payload Delivery Polymersomes are a type of nanoscale vesicle made from block copolymers and can encapsulate a variety of therapeutic agents including proteins and nucleic acids. These nanovesicles are assembled at room…
Technology Process for the Low Cost and Non-Toxic Isolation of Cellulose Nanofibers from Grass Biomass Cellulose nanofibers are a class of nanocellulose that are favored in materials applications because of their desirable chemical, mechanical, and environmental properties. However, the isolation of these materials from biomass…
Technology Doped Silicon Nanowires for the Selective Modulation of Single-cells Electric stimulation of organs with implantable devices has demonstrated clinical utility for the treatment of a variety of diseases such as cardiac arrythmia. However, use of these technologies remains high…
Technology Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes Quantum nanoprobe system enables real-time probing of intracellular chemical environments and activity to advance biological and medical diagnostics The Unmet Need: Novel ways to probe cellular processes and improve biological…
Technology Engineered Cardiac Microtissues Using Trace Silicon Nanowires To Improve Functional Maturity A trace amount of electrically conductive silicon nanowires (e-SiNWs) into otherwise scaffold-free hiPSC-derived cardiomyocyte spheroids to improve electrical coupling, synchronized beating, calcium handling, and structural maturation. The Unmet Need: Human…
Technology Redox-Controlled Molten-Salt Cation Exchange for Tunable Multicomponent III-V Quantum Dots This technology achieves enhanced chemical stability and compositional control of reactive III-V colloidal nanocrystals by employing reduced molten salts as solvents, thereby overcoming decomposition issues and enabling synthesis of novel…
Technology AuNP-DG: Deoxyglucose Labeled Gold Nanoparticles as X-Ray Computed Tomography Contrast Agents for Cancer Imaging The targeted metabolic imaging enhancement achieved by deoxyglucose-labeled gold nanoparticles (AuNP-DG) offers superior tumor-specific contrast and improved resolution in computed tomography (CT) scans compared to conventional iodine-based agents, facilitating enhanced…
Technology Nanotraps for the containment and clearance of SARS-CoV-2 Inventors devised a nanomedicine termed “Nanotraps” that can completely capture and eliminate SARS-CoV-2 by triggering macrophages to engulf and clear the virus without becoming infected. Ex vivo lung perfusion system.…
