Technology Activity-responsive Split RNA Polymerase Platform for Biosensors and Gene Therapy An understanding of protein-protein interactions (PPIs) is critical to uncovering new disease pathophysiology and for developing small molecule and antibody treatments. Problematically, current approaches to assay PPIs are limited by…
Technology Depalmitoylation Chemical Probes Protein palmitoylation is a post translational modification of cystine protein residues, the dysregulation of which is implicated in diseases such as Alzheimer’s, cancers, and Huntington’s. Despite the importance of palmitoylation,…
Technology A Versatile and High-throughput Assay for the Directed Evolution of Reverse Transcriptases to Profile Epigenetic Modifications With NGS Engineered reverse transcriptases (RTs) to profile epigenetic modifications have numerous advantages over traditional antibody enrichment methods including: single base pair resolution, lower sample quantities needed, and lower noise and background…
Technology Programmable Translational-Activating RNA Therapeutic Platform Technology Many human diseases arise from insufficient protein levels, often due to genetic mutations that result in haploinsufficiency or loss of protein function. Effectively treating these conditions necessitates therapeutic strategies capable…
Technology Point Of Care Monitoring Of Inflammatory Diseases A quantitative method of calprotectin measurement from various biological samples to monitor disease severity, progression, and effectiveness of treatment interventions in inflammatory diseases. The Unmet Need: A simple and quantitative…
Program New Venture Challenge Launch and grow a company through the University’s nationally recognized startup accelerator program with four specialized tracks.
News These UChicago Students Want to Make it Easier for Political Activists to Organize With politics being one of the most contentious topics in America right now, ordinary citizens are engaging in activism efforts in increasing numbers, and this Chicago startup wants to help....
News Polsky Center Announces 2018 Summer Accelerator Cohort The Polsky Center for Entrepreneurship and Innovation is pleased to announce the latest cohort of the Polsky Accelerator, a 10-week intensive summer program designed for both for-profit and not-for-profit startups to...
News Polsky Accelerator Program Concludes with Demo Day For the past 10 weeks, 14 companies have participated in the 2018 Polsky Accelerator program. The annual program is designed for both for-profit and not-for-profit startups to develop their ventures....
News The Modern-day Explorer: Chicago Booth Alum Turns to Deep-tech Innovations to Save the World When you talk to Bryan Johnson, MBA ’07, about his current work, he brings up the year 1978. The late-70’s saw the beginnings of companies such as Apple, Intel, Microsoft,...
News Polsky Center Announces Winter 2019 I-Corps Program Cohort The Polsky Center is pleased to announce the latest cohort of the Polsky I-Corps program.
