Technology Flexible, AI-Enabled Wearables for Precision Medicine This technology enables on-body AI data analysis of data from skin-like wearable electronics for achieving human-integrated/mimetic intelligent systems. The Unmet Need: Data processing for precision medicine Precision medicine, the future…
Technology Bio-inspired Artificial Intelligence For Rapid Multi-Task Learning Multi-task learning is a subfield of machine learning in which multiple tasks are simultaneously learned by a shared model. Biologically-inspired recurrent neural networks (RNNs), trained using backpropagation, can learn an…
Technology Co-intercalation-free Ether Solvent for Lithium Ion Batteries Lithium-ion batteries have revolutionized portable electronics, but there remains room for improvement in energy density, electrochemical stability, and usable temperature window. An improvement in electrolytes can further such needs for…
Technology Fully Synthetic Adjuvant Delivery System For Enhanced Tumor-Targeted Immunotherapy A cancer vaccine that enhances immune response by directly binding adjuvants to tumor cells, avoiding targeting antibodies, and reducing related side effects The problem: Therapeutic vaccination has long been a…
Technology Engineered Flt3L Variants For Antigen Tolerance Induction Engineered recombinant fusion of the dendritic cell growth factor Flt3L to serum albumin to modulate the antigen-presenting compartment and bias it toward tolerance particularly against therapeutic proteins. The Unmet Need:…
Technology Method to Integrate Diamond with Other Functional Materials for Quantum Technologies Keywords: Quantum Information, Spin Coherence, Condensed Matter, Solid State Qubits This technology enables diamond to be integrated with other functional materials enabling the fabrication of diamond-based heterostructures, which are ideal…
Technology DeMaND (Decoding using Manifold Neural Dynamics) This method enables high fidelity decoding of neural activity in an interpretable manner with a small training data set. The Unmet Need: Measuring neural activity in the brain with a…
Technology Novel RNA Replicon Vector For Efficient Gene Delivery To The Skin A Sindbis virus-based self-amplifying RNA vector has been engineered for long-lasting, safe gene expression in skin cells, aiming to treat genetic skin disorders like recessive X-linked ichthyosis by restoring missing…
Technology Nanoscale Metal-Organic Frameworks For X-Ray Triggered Combination Cancer Therapy A nanoscale metal-organic framework uses heavy metals to enhance X-ray absorption, triggering prodrug activation for precise cancer treatment by combining radiotherapy, chemotherapy, and immunotherapy with reduced systemic toxicity. The Unmet…
Technology Type I Interferons For Enhancing Chimeric Antigen Receptor T-Cell Efficacy Method to enhance CAR T-cell efficacy by incorporating low-dose exogenous IFN-α2 into CD19-directed, CD28-costimulated CAR T cells post-transduction during manufacturing boosting cytolytic molecule expression, cytokine secretion, and cytotoxicity while minimizing…
Technology Computerized Adaptive Testing System For Real-Time Multidimensional Fatigability Assessment A computerized adaptive test using a bifactor model on tablet devices to measure fatigue relative to activity delivering personalized, real-time insights by integrating with electronic health records, helping clinicians make…
Technology A Next-Generation mRNA Vaccine Platform For Enhancing T-Cell Responses And Improving Antiviral And Antitumor Immunity Next-generation mRNA vaccine platform uses a lipid-polymer hybrid nanoparticle to boost stability, immune cell uptake, and T cell responses, leading to stronger and longer-lasting protection against viruses and cancer while…
