Technology A Targeted Radiopharmaceutical Platform For Improving Diagnosis And Treatment Of Neuroendocrine Tumors Advanced imaging and targeted radiotherapy for neuroendocrine tumors, using DOTATATE-based agents for precise diagnosis and treatment, and enhancing therapy effectiveness by adding Fulvestrant as a radiosensitizer to further reduce tumor…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
News Entrepreneurship in Africa Has “Big Risks” and “Big Payoffs.” Here’s How Ugandan Businessman Aga Sekalala Jr. Found Success. The Polsky Center’s Distinguished Entrepreneur speaker series this month featured Aga Sekalala Jr., a prominent Ugandan businessman who founded Radio Simba, one of the most popular broadcasters in East Africa,...
Technology Targeting TGFβ Signaling for Enhancing Cancer Radiotherapy and Immunotherapy Efficacy The method leverages a negative regulator to inhibit TGFβ signaling in myeloid cells, potentially enhancing the efficacy of radiotherapy and immunotherapy in cancer treatment by reducing immune suppression. The problem:…
Technology Boosting Cancer Immunotherapy Or Radio-Immunotherapy For Enhanced Tumor Eradication New cancer therapy to enhance the efficacy of checkpoint inhibitor immunotherapy and radiation by blocking tumor-promoting signals from erythroid progenitor cells, which secrete artemin to advance cancer progression. This approach…
News Meet the Transform Cohort 2 Startups: RadioLogical.ai Team Members Gerardo Chaquinga – Chief Executive Officer & Cofounder Tarun Gulrajani – Chief Strategy Officer & Cofounder Raul Albertti C. – Chief Technology Officer & Cofounder Martin Carnier –...
Page Venture Gallery Venture Gallery View startups founded from across the University of Chicago ecosystem in a range of industries. Welcome to the Venture Gallery! The Polsky Center provides “first look” and early...
Technology Nanoscale Metal-Organic Frameworks For X-Ray Triggered Combination Cancer Therapy A nanoscale metal-organic framework uses heavy metals to enhance X-ray absorption, triggering prodrug activation for precise cancer treatment by combining radiotherapy, chemotherapy, and immunotherapy with reduced systemic toxicity. The Unmet…
Technology Next-Generation Activity-Based Radiotracer For In Vivo Positron Emission Tomography (PET) Imaging And Therapy Cancer cells show alterations in metabolism that support malignancy and disease progression. Prominent among these metabolic changes is elevations in neutral ether lipids (NELs). The lipid hydrolase neutral cholesterol ester…
Technology Small Molecule Inhibitor Boosting The Efficacy Of Therapeutic Ionizing Radiation Radiotherapy and immunotherapy are used to treat many cancer types, yet only 50% and 20% of patients respond, respectively. Resistance to therapy presents a large problem. N6-methyladenosine (m6A) modification is…
Event Polsky Exchange Member Breakfast and Professional Headshots April 29, 2026 This month’s Exchange member breakfast brings together our community of entrepreneurs and innovators for an exchange of ideas, networking, and collaboration. Connect with fellow members, share insights, and foster meaningful...
Technology Computational Method to Design Simultaneous Radiation Treatment of Multiple Metastatic Lesions Stereotactic ablative body radiotherapy (SART) is the precise delivery of concentrated radiation beams to a tumor from different angles. Due to the cross interaction between beams, SART is rarely able…
