News UChicago’s Chuan He Recognized for Real-World Impact of Research University of Chicago researcher Chuan He has been recognized for the potential real-world impact of his work – including a method to dramatically increase crop yields and an innovative liquid...
Technology In Vitro Assay To Select Optimal Small RNA Guides To Redirect ADAR (Adenosine Deaminase That Acts On RNA) Enzymes A breakthrough method to systematically select for optimal small guide RNAs using an unbiased approach for improved accuracy and efficiency of all systems of site-directed RNA editing. The Unmet Need:…
Technology Small Molecule Splicing Modulators For Reducing Aggregatable Prion Protein In Prion Diseases First-in-class small molecules to change how the PRNP gene is spliced, reducing harmful prion levels and offering a new treatment approach for prion diseases The Unmet Need: Safe, effective,…
Technology Enhanced Vaccine Efficiency via an Antigen Targeting, Immune Stimulating Co-polymer Vaccine efficacy is limited due to the inability to deliver in-tact antigens to antigen presenting (APC) dendritic cells (DCs) while simultaneously activating the cells in a non-toxic fashion. Adjuvants have…
Technology Laser-Patterned Nitrogen-Doped Silicon Carbide For Organ-On-Chip And Bioelectric Applications A laser-writing process converts selected regions of PDMS into nitrogen-doped cubic silicon carbide with an integrated graphite layer, producing flexible semiconductor biointerfaces that can be patterned in 2D or formed…
Technology Tunable High-Q Superconducting mm-Wave Cavities Cavity and circuit quantum electrodynamics systems provide unprecedented control over photonic quantum states via coupling to strongly nonlinear single emitters. The millimeter (mm) wave frequency band is of great interest…
