Technology Synthetic Monoclonal Antibodies For Blocking Human Growth Hormone Receptor Signaling Synthetic monoclonal antibodies using phage display to bind and block the human growth hormone receptor, potentially offering a more potent and specific treatment for conditions like acromegaly by inhibiting receptor…
Technology A Biomarker Analysis Platform For Predicting Immunotherapy Response And Survival In Cancer Patients A method using tumor sequencing data to measure membrane-localized neoantigens, helping predict which cancer patients will benefit from immunotherapy, even those with low tumor mutational burden, improving treatment selection and…
Technology Computational-Guided Spin Defect Systems This method enables predictive growth of qubit host materials without the limitations of iterative measurements. The Unmet Need: Proper characterization of qubit host substrate and in-situ defect growth Quantum sensors…
Technology Antibody-Based Therapeutics For Inhibiting Growth Hormone Receptor Dimerization And Signaling Antibodies that block growth hormone signaling by binding the receptor or hormone to stop receptor pairing, based on high-affinity, defined sequences for therapeutic and research use. The Unmet Need: Effective…
Technology COMT inhibitors for impulsive behaviors Drug repurposing to use catechol-O-methyl-transferase inhibitors for treating impulse control disorders, obsessive-compulsive disorders, and substance addictions The Unmet Need: New options for treating impulsive behavior disorders Impulse control disorders, Obsessive-Compulsive…
Technology New Class of Biocompatible and Flexible Optoelectronic Devices For Next Generation Pacemakers Electrode-based electrical stimulation underpins several clinical bioelectronic devices, including deep brain stimulators and cardiac pacemakers. Pacemaker therapy improves quality of life and reduces mortality rates. Despite significant advances, current pacemaker…
Technology A Targeted Radiopharmaceutical Platform For Improving Diagnosis And Treatment Of Neuroendocrine Tumors Advanced imaging and targeted radiotherapy for neuroendocrine tumors, using DOTATATE-based agents for precise diagnosis and treatment, and enhancing therapy effectiveness by adding Fulvestrant as a radiosensitizer to further reduce tumor…
Technology Multihydroxy-Propane Vesicle System and Method for Topical Delivery of mRNA Groundbreaking advancement in the field of mRNA topical delivery systems, providing superior penetration, stability, and biocompatibility compared to existing solutions. It opens up new possibilities for both therapeutic and cosmetic…
Page About Us about us Advancing innovative ideas and technologies from the University of Chicago ecosystem to the world. The Polsky Center’s roots trace back to the University of Chicago’s longstanding commitment to...
Event UChicago Science Incubator One-Year Anniversary Celebration June 16, 2026 Join us as we celebrate the 1-Year Anniversary of the UChicago Science Incubator, a milestone marking a year of innovation, collaboration, and groundbreaking discovery. This special celebration will feature networking,...
News The Polsky Center Announces the 20 Startups Selected for India Deep Tech Accelerator The Polsky Center for Entrepreneurship and Innovation today announced the 20 startups selected to join the inaugural cohort of the India Deep Tech Accelerator, a global accelerator designed to help high-potential, Indian...
News 10 Startups to Compete for Over $1 Million at 30th Annual Edward L. Kaplan, ’71, New Venture Challenge Finals The Polsky Center for Entrepreneurship and Innovation today announced the 10 teams advancing to the finals of the 30th annual Edward L. Kaplan, ’71, New Venture Challenge (NVC), the Chicago Booth School...
