Technology Q11: a Highly Homogeneous Multivalent and Single-component Vaccine Adjuvating Platform There is a limited choice in clinically approved adjuvants for vaccine development. Current solutions are themselves immunogenic, causing injection site swelling and reactions. The inventors developed a 15 amino acid…
Technology Novel Compounds for the Potentiation of Antibiotic Resistance in Staphylococcus Aureus Currently there is no available vaccine for the prophylaxis of S. Aureus mediated infections such as MRSA, and antibiotics such as beta lactams and oxacillin are most commonly used for…
Technology Thermonobodies: A Novel Thermostable FN3 Binding Protein Scaffold Monobodies are synthetic binding proteins based off a human fibronectin type 3 (FN3) scaffold that have demonstrated their utility in applications such as the modification of enzyme specificity and therapeutics…
Technology An Innovative Cutaneous Gene Therapy Platform For Metabolic Disorders The field of metabolic disease treatment has long been challenged by the need for precise, long-term regulation of critical hormones and proteins that manage glucose homeostasis and energy balance. Current…
Technology A Highly Efficient Spatial and Temporal Method for Isotopic Separation Present isotope separation methods utilize laser beams, centrifugation, and diffusion to exploit subtle differences in physical properties. However, these methods are relatively inefficient and require multiple successive steps to achieve…
Technology Simultaneous Acquisition of Myocyte Oxygen Usage and Cardiac Strain Data in a Single MRI Scan Abnormal myocardial oxygen usage can predict heart attack or heart transplant rejection before the onset of clinical symptoms. However, there are currently no robust and reliable methods for globally measuring…
Technology CAR T-Cells That Recognize Cancer-specific Glycopeptides Across Multiple Cancer Types The development of cancer immunotherapies is limited by a lack of targetable tumor antigens. Most currently targeted antigens have basal expression in healthy tissue, which results in potentially life threatening…
Technology Neurophysiological Biomarker for Early ALS Detection Presently, physicians rely on a costly and invasive battery of tests for diagnosing ALS. Early detection of ALS can improve patient survival and quality of life as well as promote…
Technology A Surgical Stent for Impermeable Anastomoses Anastomotic leak is a serious complication of gastrointestinal surgery, with consequences ranging from benign to life threatening. Treatment is costly and exposes patients to additional pain and risk. Current common…
Technology Functionalized Molybdenum Disulfide Membranes For Water Filtration The invention is a method to fabricate membranes made from exfoliated molybdenum disulfide (MoS2) for improved separation performance and membrane stability. Reverse osmosis (RO) membranes are undergoing widespread adoption in…
Technology Novel Small Molecules For Treatment Of Breast and Ovarian Cancer According to the National Osteoporosis Foundation (NOF) approximately 10.2 million adults in the United States have osteoporosis, with an additional 43.4 million having low bone mass. One in eight women…
Technology Improved Electrochemical Li Extraction From Seawater And Other Dilute Li Sources Using Mixed Li An Na Layered Oxides Use of Li in electric vehicle batteries, portable electronic devices, and stationary energy storage applications has expanded significantly in recent years, and this growth is expected to continue to increase. …