Technology Fatty acids In T Cell-Based Cancer Therapies Enhanced anti-tumor immunity through immunomodulation is achieved by fatty acids that activate CD8+ T cells, thereby improving cancer immunotherapy efficacy and reducing T-cell exhaustion. The Unmet Need: Limited effectiveness of current…
Technology Rapid Selection Of High-Value Internalizing Binders For Targeted Therapeutics Lentiviral display platform engineered to directly select and enrich antibodies based on their ability to induce receptor-mediated endocytosis, thereby streamlining the discovery of highly internalizing candidates for targeted therapies The…
Technology Real-Time High-Definition Mapping Platform For Complex Cardiac Arrhythmia Intervention A novel high-resolution mapping platform offering real-time blockline angle, crossing point analytics, and fiber orientation visualization to enable targeted arrhythmia intervention and improved ablation outcomes. The Unmet Need: Current mapping…
Technology Ultrathin, Plasmonic Schottky Biointerfaces For Wireless Stimulation And Sensing A plasmon-enhanced hierarchical gold–titania (Au-TiO₂) Schottky junction biointerface designed for wireless, energy-efficient biological stimulation (neuromodulation, cardiac pacing), real-time biosensing, and minimally invasive artificial vision. The platform is scalable, CMOS-free, and…
Technology Next-Generation Minimally Invasive Optoelectronic Implants For Chronic Disease Management The platform delivers ultra-low intensity, wireless, fully implantable photostimulation for deep tissue targets (nerves, heart, diaphragm). It spatially separates light harvesting from bioelectrical stimulation, enabling minimally invasive, leadless, genetic-modification-free interventions.…
Technology Lithium-Driven Neural Inhibition Devices For Chronic Pain And Local Anesthesia An implantable bioelectronic device platform enabling targeted, programmable inhibition of neural activity through lithium ion delivery, offering durable local anesthesia and pain relief without systemic toxicity The Unmet Need: Programmable…
News Rattan L. Khosa Took a Risk to Build Something New and Now Helps NVC Founders Do the Same Rattan L. Khosa speaks to the students at SeedCon 2025. As part of the NVC@30 celebration, Rattan L. Khosa, ’79, reflected on his entrepreneurial journey, his connection to Booth, and...
Program ETA Advisory Committee Comprised of leading operators, investors, and academics in the ETA space, the Polsky Center ETA Advisory Committee is instrumental in providing guidance to the growth and impact of our ETA...
Technology Zero-burden Risk Assessment (ZeBRA) Platform for Point-in-care Universal Screening of Complex Disorders ZeBRA is a software-based platform for universal, point-of-care risk screening that uses existing EHR data to identify patients at elevated risk for complex disorders such as Alzheimer’s disease and related…
Program Past Participants 2025 Folasade Rancie – Doulala Michael Gustafson – Three Pillars Sudanshu Kaushik – Exalt Data Randel Bennett – Qixent Laurel Alpaugh – Coclo Ritu Sreenivasan – Mooj Foods Shikhar Pandey…
Technology Modular Glycopolymer Technology for Antigen-Specific Immune Tolerance This technology achieves significant reduction of anti-drug antibody responses through synthetically mannosylated antigen conjugation that induces antigen-specific humoral tolerance by enhancing hepatic immune tolerance mechanisms. The Unmet Need: Effective mitigation of…
Technology Integration Of Semiconductor-Based Components And Functionality Into Soft Microfluidics For Cell Lysis And Other Biological Applications This technology delivers precise and scalable cellular content extraction for genomic analyses by integrating semiconductor-based piezoelectric sharp tip arrays into soft microfluidics, enabling efficient mechanical cell lysis, particularly of hard-shelled…
