News How to Launch Your Business-to-Consumer Business This Year The following article was written by Mia Saini Duchnowski, entrepreneur-in-residence at the Polsky Center, and originally published in Crain’s Chicago Business on April 15, 2024. Read the original article. One...
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Technology Novel Use of a Bet Bromodomain Protein Inhibitor (JQ1) for the Treatment of Sickle Cell Anemia and Thalassemia Embryonic and fetal hemoglobin have a higher affinity for oxygen than their adult counterpart, and as such, gene editing techniques to revert red blood cells to produce infant or fetal…
Technology RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise and effective leukemia treatments The Unmet…
News Innovation Fund Targets Leukemia “This award will permit us to build upon our preliminary data to facilitate the development of a promising new strategy to treat acute leukemia.” So says Michael J. Thirman, MD,...
News Rattan L. Khosa SeedCon 2024: Innovating Amongst Giants in a Down Economy Last week, the Polsky Center and Chicago Booth’s Entrepreneurship and Venture Capital (EVC) Group co-hosted Rattan L. Khosa SeedCon 2024, Booth’s annual flagship entrepreneurship and venture capital conference. Through keynote...
Technology Novel TET2-Targeting Approaches to Induce Fetal Hemoglobin in Sickle Cell Disease and Thalassemia This technology enables increased fetal hemoglobin production to alleviate symptoms of blood disorders by modulating TET2 enzyme activity through targeted mutation and pharmacological suppression. The Unmet Need: Insufficient fetal hemoglobin…
Technology Real-Time High-Definition Mapping Platform For Complex Cardiac Arrhythmia Intervention A novel high-resolution mapping platform offering real-time blockline angle, crossing point analytics, and fiber orientation visualization to enable targeted arrhythmia intervention and improved ablation outcomes. The Unmet Need: Current mapping…
News Immunoengineering Conference to Highlight the Latest Developments in Industry, Academia, and UChicago Startups The Pritzker School of Molecular Engineering’s Chicago Immunoengineering Innovation Center (CIIC) in partnership with the Polsky Center for Entrepreneurship and Innovation is hosting Immunoengineering 2021 – which will highlight the...
News Academia and Private Sector Meet at 10th Annual Entrepreneurship Through Acquisition Conference The Polsky Center, in collaboration with the Chicago Booth School of Business and Northwestern Kellogg School of Management, hosted the 10th annual Booth-Kellogg Entrepreneurship Through Acquisition (ETA) Conference this week....
Technology Hydrogel Electrochemical Platform For Controlled Localized Hydrogen Delivery A portable device that generates and stores molecular hydrogen within a hydrogel using electrodes to precisely deliver hydrogen locally to treat oxidative stress in skin diseases and ischemia-reperfusion injuries The…
