Technology Fully Synthetic Adjuvant Delivery System For Enhanced Tumor-Targeted Immunotherapy A cancer vaccine that enhances immune response by directly binding adjuvants to tumor cells, avoiding targeting antibodies, and reducing related side effects The problem: Therapeutic vaccination has long been a…
Technology DeMaND (Decoding using Manifold Neural Dynamics) This method enables high fidelity decoding of neural activity in an interpretable manner with a small training data set. The Unmet Need: Measuring neural activity in the brain with a…
Technology Targeting TGFβ Signaling for Enhancing Cancer Radiotherapy and Immunotherapy Efficacy The method leverages a negative regulator to inhibit TGFβ signaling in myeloid cells, potentially enhancing the efficacy of radiotherapy and immunotherapy in cancer treatment by reducing immune suppression. The problem:…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
Technology Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes Quantum nanoprobe system enables real-time probing of intracellular chemical environments and activity to advance biological and medical diagnostics The Unmet Need: Novel ways to probe cellular processes and improve biological…
Technology RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise and effective leukemia treatments The Unmet…
Technology Palm-Free Haptics: Full-Hand Touch Feedback for VR/AR and Wearable Interfaces Summary University of Chicago researchers have developed a wearable electro-tactile feedback technique that creates touch sensations across the palm and fingers without placing electrodes directly on the palm. By positioning…
News UChicago Deep Tech Demo Day Showcases Emerging Ventures During TechChicago Week Last week the Polsky Center for Entrepreneurship and Innovation hosted founders, investors, faculty, corporate partners, and ecosystem leaders for the UChicago Deep Tech Demo Day.
News Small Business Spotlight: Kabob-It Turns Global Flavors into an Expanding Food Concept Kabob-It, a restaurant in Hutchinson Commons on the UChicago campus that pairs Mediterranean cuisine with African American culinary influences and a growing range of flavors from around the world.
News Out of the Lab: Business Course Gives Scientists Opportunity to Explore Entrepreneurship The Entrepreneurship for Science and Medicine course gives University of Chicago graduate students, postdocs, and faculty the opportunity to explore the intersection of science and business. Taught by Chicago Booth...
Page In-Kind Resources for UChicago Student Founders To help founders accelerate their progress, the Polsky Center has partnered with several external organizations to offer free and discounted resources for University of Chicago students. Inclusion on this list...
Event Entrepreneurship Essentials (E2): Customer Discovery for Startups with Melissa Byrn November 10, 2026 Join the Polsky Center and Melissa Byrn, Assistant Dean for Clinical Research at the University of Chicago Biological Sciences Division, for an informative workshop on early stage customer discovery for...
