Technology Zero-burden Risk Assessment (ZeBRA) Platform for Point-in-care Universal Screening of Complex Disorders ZeBRA is a software-based platform for universal, point-of-care risk screening that uses existing EHR data to identify patients at elevated risk for complex disorders such as Alzheimer’s disease and related…
News Chicago Innovation Mentors Celebrates First Year A superhighway runs into Chicago’s leading universities, carrying innovative scientists, talented students and significant research funds, says John Flavin, the new executive director of Chicago Innovation Mentors (CIM). “We need...
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Technology Point Of Care Technology For SARS-CoV-2 Detection and Neutralization SARS-CoV-2’s enters cells when the receptor binding domain (RBD) of its spike protein (S-protein) interacts with angiotensin-converting enzyme 2 (ACE2). In order to block this RBD-ACE2 interaction, clinicians need Point…
Technology Patient Microbiota As A Predictive Biomarkers For Response To Checkpoint Blockade Therapy Improved prediction of patient response to checkpoint blockade immunotherapy through identification of specific gut microbiota biomarkers, thereby enhancing clinical decision-making and treatment efficacy in oncology. The Unmet Need: Reliably predicting immunotherapy…
News Kompass Diagnostics Points the Way to Better Fertility Care with Novel Finger-Prick Hormone Testing [Update: Since this article was published, Kompass Diagnostics was selected to receive the 2026 Association for Diagnostics and Laboratory Medicine (ADLM) Disruptive Technology Award. The team also took home the...
News 18 Teams Selected for Classroom Portion of the 19th Annual Global New Venture Challenge From Chicago, Hong Kong, and London, 18 teams are advancing to the classroom portion of the Polsky Center for Entrepreneurship and Innovation’s 2026 Global New Venture Challenge (GNVC). Now...
Technology RNA Editing Technology for Enhancing Tumor Immunogenicity and Immune Checkpoint Inhibitors Novel RNA editing method to generate a multitude of neoantigens in tumor cells making the cells more recognizable by T cells and enhancing the efficacy of immune checkpoint inhibitors The…
Technology Point Of Care Monitoring Of Inflammatory Diseases A quantitative method of calprotectin measurement from various biological samples to monitor disease severity, progression, and effectiveness of treatment interventions in inflammatory diseases. The Unmet Need: A simple and quantitative…
News Rattan L. Khosa SeedCon 2026: Beyond the Hype Last week, the Polsky Center for Entrepreneurship and Innovation and Chicago Booth’s Entrepreneurship and Venture Capital (EVC) Group hosted the Rattan L. Khosa SeedCon 2026, the University of Chicago’s flagship...
News Buoyed by Insiders, Flagship’s Evelo Hits Midpoint of IPO Range Evelo Biosciences, a biotech company based on technology licensed through the Polsky Center from UChicago Medicine’s Thomas Gajewski, debuted on Nasdaq. Read the full article >>
Technology Next-Generation Immunotherapy Platform With Engineered Collagen-Binding Cytokine Combinations Combination engineered IL-7 and IL-12 proteins that target tumors by binding to collagen, boosting immune attack on cancer while reducing side effects and improving long-term protection, even in cancers resistant…