Technology Novel Nano-Formulation For Multi-TLR Agonists To Boost Immune Responses Against Solid Tumors Toll-like receptor (TLR) agonists are considered promising alternatives for the estimated 50 – 75% of all cancer patients who are non-responsive to checkpoint inhibitors, and immune activation is enhanced upon…
Technology Diagnostic For Predicting Hospital-Acquired Infections And Identifying Causative Organisms The technology is a fecal microbiome metabolite profile that can predict hospital-acquired infections and identify the causative organisms. This method efficiently measures specific chemical metabolites produced by bacteria in the…
Technology A Metal Organic Framework (MOF) Containing Nitrogen Donor Ligands For Highly Efficient Catalysis of Organic Reactions Pyridyl moieties are highly useful in catalytic applications because of their robust redox stability, metallic coordination versatility, and functionalization ease. However, their application is limited due to poor solubility and…
Technology A Biomarker Platform for Predicting Carboplatin Sensitivity and Enabling Targeted Ovarian Cancer Immunotherapy The field of oncological diagnostics and therapeutics has long sought methods to refine treatment approaches for aggressive cancers. In conditions such as advanced high-grade ovarian cancer, there is a critical…
Technology An Innovative Cutaneous Gene Therapy Platform For Metabolic Disorders The field of metabolic disease treatment has long been challenged by the need for precise, long-term regulation of critical hormones and proteins that manage glucose homeostasis and energy balance. Current…
News Polsky Center Announces 2018 Summer Accelerator Cohort The Polsky Center for Entrepreneurship and Innovation is pleased to announce the latest cohort of the Polsky Accelerator, a 10-week intensive summer program designed for both for-profit and not-for-profit startups to...
Technology Novel Delivery Platform For Controlled Release Of Bacterial Metabolites To Modulate The Immune System Conditioning of the immune system by the microbiome has received substantial attention for the scientific community in recent years. Microbial metabolites are being assessed as novel therapeutic tools for various…
Program Our Process and Advisory Committee Our Process The George Shultz Innovation Fund invests in promising startups from an ecosystem that includes the University of Chicago, Argonne National Laboratory, Fermilab, and the Marine Biological Laboratory. The...
Technology Real-Time High-Definition Mapping Platform For Complex Cardiac Arrhythmia Intervention A novel high-resolution mapping platform offering real-time blockline angle, crossing point analytics, and fiber orientation visualization to enable targeted arrhythmia intervention and improved ablation outcomes. The Unmet Need: Current mapping…
News Can Entrepreneurship Help Revive Syria? This Polsky Center Leader is Training Teens in Business Chicagoan Steve Lehmann has taken his expertise in early business development nearly 6,000 miles away to the Turkish border town of Reyhanli. His mission: to teach Syrian teens how to...
News UChicago Invests in “RegTech” Company Founded by Chicago Booth Alums The University of Chicago has announced their next venture investments from the UChicago Startup Investment Program. Ascent Technologies, a regulation technology company that helps users build, manage, and automate their...
