Technology Single-Step Method For Assembling Free-Standing Lipid Bilayers In Holey Grids For Cryo-EM Of Membrane Proteins Simplified approach to assemble free-standing lipid bilayers with membrane proteins in holey carbon grids directly usable for cryo-EM with high resolution The Unmet Need: Novel technique to achieve high-resolution…
Technology A Gene-Modified T Cell Platform For Spatially Controlled Therapeutic Protein Delivery In Response To Radiation Engineered T cells to release cancer-killing proteins only when activated by targeted radiation, enabling precise, localized tumor treatment while minimizing side effects and improving the effectiveness of CAR-T therapy for…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
Technology Reversible Gene Editing System For Site-Specific Large DNA Integration And Excision The Unmet Need: Methods for efficient, reversible integration and excision of large DNA Genome engineering is a rapidly advancing field with immense potential for synthetic biology and gene therapy. The…
Technology A Transcriptomic Signature Platform For Predicting Prognosis And Guiding Therapy In Ovarian Cancer Patients A 10-gene signature based on glucocorticoid receptor activity to predict survival risk in high-grade serous ovarian cancer patients, helping identify those who may benefit from specific therapies and improving personalized…
Event Distinguished Entrepreneur Series: Greycroft and Apax Partners Cofounder Alan Patricof February 23, 2023 Join the Polsky Center for Entrepreneurship and Innovation at the University of Chicago for a Distinguished Entrepreneur Speaker Series Event featuring Apax Partners Founder and Greycroft Cofounder, Alan Patricof, in...
News From Mississippi to the Last Frontier: Ben Frazer’s Path to ETA in Alaska Growing up in a small town in Mississippi, entrepreneurship was close to home for Ben Frazer, MBA ’25. His father founded a business in 2000, and from an early age...
News Third Coast Foundry Celebrates Grand Opening, Showcases 40 Deep Tech Startups at Demo Day The Polsky Center for Entrepreneurship and Innovation, along with the seven other university partners that make up Third Coast Foundry, marked the official launch of the new San Francisco-based innovation...
News The Polsky Center to Support Quantum Ecosystem as Part of $55M Bloch Quantum Tech Hub Initiative The Polsky Center for Entrepreneurship and Innovation will provide resources to help quantum companies grow as part of a new $55 million effort to build a domestic quantum supply chain...
News From New Locations to Million-Dollar Grants, Polsky Small Business Growth Program Alumni Continue to Grow Alumni of the Polsky Small Business Growth Program are marking a series of major milestones, from opening additional locations to securing grants and contracts worth more than $1M.